FE65 Proteine
(Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012].
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custom-made
APBB1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
APBB1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
APBB1
Spezies: Human
Wirt: Wheat germ
Recombinant
ELISA, WB, AA, AP
1 image
custom-made
APBB1
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
APBB1
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
APBB1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
1 image
APBB1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
APBB1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliase für FE65 Proteine
amyloid beta precursor protein binding family B member 1 (APBB1) Proteineamyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog (apbb1.L) Proteine
amyloid beta (A4) precursor protein-binding, family B, member 1 (Apbb1) Proteine
amyloid beta precursor protein binding family B member 1 (Apbb1) Proteine
apbb1 Proteine
FE65 Proteine
Fe65 Proteine
MGC80654 Proteine
MGC:9072 Proteine
RIR Proteine
Rir Proteine
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