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PLAT Proteine

(Plasminogen Activator, Tissue (PLAT))
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding\; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

41 Treffer

PLAT Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % AcA, CC Active
Produktnummer ABIN6238250
842,00 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach: Deutschland
Lieferung in 13 bis 17 Werktagen
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • ELISA
    • Activity Assay (AcA)
    • Cell Culture (CC)
    • Antibody Production (AbP)
    • Biochemical Assay (BCA)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Pig
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • HEK-293F Cells
    • Baculovirus infected Insect Cells
    • Bacteria
    • Mammalian Cells
    • Eukaryota
    • Human
    • Human Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 311-562
    • AA 33-559
    • AA 359-532
    • AA 36-562
    • AA 309-559
    • AA 36-126
    • partial
    • AA 1-562
    • AA 18-559
    • AA 23-562
    • AA 24-562
    • AA 311-487B
    • AA 311-561
    • AA 316-559
    • AA 36-310
    • AA 36-556
    • AA 37-310
    • AA 39-562
    • Chain alpha
    • Chain beta
    • Transcript Variant 3
  • Konjugat
    • His tag
    • Unkonjugiert
    • His tag,GST tag
    • Fc Tag
    • Fc-His Tag
    • His-SUMO Tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • hFc Tag
  • Protein-Typ
    • Recombinant
    • Native
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • Signalway
    • Cloud-Clone
    • ProteoGenix
    • CUSABIO
    • OriGene

Aktuelle Publikationen für unsere PLAT Proteine

Wang, Luo, Masci, Crawford, Xiao: "Influence of Interleukin-1 Beta on Platelet-Poor Plasma Clot Formation: A Potential Impact on Early Bone Healing." in: PloS one, Vol. 11, Issue 2, pp. e0149775, (2016) (PubMed).

Bongoni, Kiermeir, Schnider, Jenni, Garimella, Bähr, Klymiuk, Wolf, Ayares, Voegelin, Constantinescu, Seebach, Rieben: "Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions." in: Transplantation, (2015) (PubMed).

Harr, Moore, Chin, Chapman, Ghasabyan, Stringham, Banerjee, Silliman: "Viscoelastic hemostatic fibrinogen assays detect fibrinolysis early." in: European journal of trauma and emergency surgery : official publication of the European Trauma Society, Vol. 41, Issue 1, pp. 49-56, (2015) (PubMed).

Kim, Tirloni, Radulovic, Lewis, Bakshi, Hill, da Silva Vaz, Logullo, Termignoni, Mulenga: "Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions." in: International journal for parasitology, Vol. 45, Issue 9-10, pp. 613-27, (2015) (PubMed).

Mantuano, Lam, Shibayama, Campana, Gonias: "The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration." in: Journal of cell science, (2015) (PubMed).

Lin, Jin, Hu: "Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7910-7, (2015) (PubMed).

Shahrour, Keck, Jankun: "Application of long-acting VLHL PAI-1 during sutureless partial nephrectomy in mice reduces bleeding." in: BioMed research international, Vol. 2015, pp. 392862, (2015) (PubMed).

Kindell, Keck, Jankun: "Comparison between the clot-protecting activity of a mutant plasminogen activator inhibitor-1 with a very long half-life and 6-aminocaproic acid." in: Experimental and therapeutic medicine, Vol. 9, Issue 6, pp. 2339-2343, (2015) (PubMed).

Chen, Chu, Brumberg: "Experience-dependent regulation of tissue-type plasminogen activator in the mouse barrel cortex." in: Neuroscience letters, Vol. 599, pp. 152-7, (2015) (PubMed).

Wu, Torre, Cuellar-Giraldo, Cheng, Yi, Bichler, García, Yepes: "Tissue-type plasminogen activator triggers the synaptic vesicle cycle in cerebral cortical neurons." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2015) (PubMed).

Aliase für PLAT Proteine

plasminogen activator, tissue type (PLAT) Proteine
plasminogen activator, tissue (Plat) Proteine
plasminogen activator, tissue type (Plat) Proteine
plasminogen activator, tissue (PLAT) Proteine
plasminogen activator, tissue (plat) Proteine
plasminogen activator, tissue type (plat) Proteine
chromosome 20 open reading frame 181 (C20orf181) Proteine
plasminogen activator, tissue L homeolog (plat.L) Proteine
AU020998 Proteine
AW212668 Proteine
D8Ertd2e Proteine
PATISS Proteine
Plat Proteine
plat Proteine
T-PA Proteine
t-pa Proteine
TPA Proteine
tPA Proteine
tpa Proteine
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