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anti-PFKFB2 (PFKFB2) Antikörper

Bezeichnung:: anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 Antikörper (PFKFB2)

Auf www.antikoerper-online.de finden Sie aktuell 120 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PFKFB2 Proteine (7) und PFKFB2 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 145 PFKFB2 Produkte verfügbar.

Synonyme:: 4930568D07Rik, PFK-2/FBPase-2, pfkfb2, RH2K, zgc:56282

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	PFKFB2	5208	O60825
	PFKFB2	18640	P70265
	PFKFB2	24640	Q9JJH5
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-PFKFB2 (PFKFB2) Antikörper

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anti-Human PFKFB2 Antikörper:

anti-Mouse (Murine) PFKFB2 Antikörper:

anti-Rat (Rattus) PFKFB2 Antikörper:

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Verknüpfte Pathways mit anti-PFKFB2 Antikörper

Regulation of Carbohydrate Metabolic Process

Weitere Produktkategorien zu PFKFB2 Antikörper

Am meisten referenzierte anti-PFKFB2 Antikörper

Human Polyclonal PFKFB2 Primary Antibody für IHC (p), WB - ABIN392769 : Yalcin, Clem, Simmons, Lane, Nelson, Clem, Brock, Siow, Wattenberg, Telang, Chesney: Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases. in The Journal of biological chemistry 2009 (PubMed)
Show all 3 Pubmed References
Chicken Polyclonal PFKFB2 Primary Antibody für WB - ABIN611038 : Cherney, McBride, Chen, Alkhatib, Bhatia, Hensley, Smulson: cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADP-ribose) polymerase. in Proceedings of the National Academy of Sciences of the United States of America 1988 (PubMed)
Show all 3 Pubmed References
Bat Polyclonal PFKFB2 Primary Antibody für WB - ABIN611039 : Duriez, Shah: Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death. in Biochemistry and cell biology = Biochimie et biologie cellulaire 1998 (PubMed)
Show all 3 Pubmed References
Human Polyclonal PFKFB2 Primary Antibody für IHC (p), ELISA - ABIN544944 : Soejima, Kawamoto, Akai, Miyoshi, Arai, Morohka, Matsuo, Niikawa, Kimura, Okubo, Mukai: Isolation of novel heart-specific genes using the BodyMap database. in Genomics 2001 (PubMed)
Show all 2 Pubmed References
Cow (Bovine) Polyclonal PFKFB2 Primary Antibody für ELISA - ABIN4344993 : Arden, Hampson, Huang, Shaw, Aldibbiat, Holliman, Manas, Khan, Lange, Agius: A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells. in The Biochemical journal 2008 (PubMed)
Human Polyclonal PFKFB2 Primary Antibody für WB - ABIN6243012 : Novellasdemunt, Tato, Navarro-Sabate, Ruiz-Meana, Méndez-Lucas, Perales, Garcia-Dorado, Ventura, Bartrons, Rosa: Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids. in The Journal of biological chemistry 2013 (PubMed)

Weitere Antikörper gegen PFKFB2 Interaktionspartner

Human 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Interaktionspartner

UCA1/miR-182/PFKFB2 axis modulates chemokine CXCL14 secretion, glycolysis and invasion of glioma cells in glioblastoma-associated stromal cells .
Crystal structure of human and cattle heart PFKFB2 and the inhibitory influence of citrate on substrate binding has been described.
Variation in PFKFB2 appears to reduce PFKFB2 expression in adipose and kidney tissues, and thereby increase risk for adiposity and diabetic nephropathy.
Highly expressed PFKFB2 protein is associated with hepatocellular carcinoma.
bifunctionality of PFK-2/FBPase-2 complements the metabolic zonation of the liver by ensuring coherent switching in response to insulin and glucagon.
amino acids stimulate Fru-2,6-P2 synthesis by Akt-dependent PFKFB2 phosphorylation and activation and show how signaling and metabolism are inextricably linked.
A persistent increase in 6-phosphofructo-2-kinase produced by a change in PFK-2/FBPase-2 isoform expression that may play an important role in the regulation of muscle glycolysis.
Suggest that PFKFB2 is not an essential upstream regulator of the anti-leukemic effects of glucocorticoids.
induction of de novo lipid synthesis by androgen requires transcriptional up-regulation of HK2 and PFKFB2, and phosphorylation of PFKFB2 generated by the PI3K/Akt signal pathway to supply the source for lipogenesis from glucose in prostate cancer cells.
Human islets expressed the PFKFB2 and PFKFB3 isoforms. PFK-2/FBPase-2 protein rather than its product fructose 2,6-P(2) is the over-riding determinant of glucose-induced insulin secretion through regulation of glucokinase activity

Mouse (Murine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Interaktionspartner

In diabetes mellitus type 1 loss of myocardial PFK-2 content as a result of reduced insulin signaling impairs the capacity to dynamically regulate glycolysis and elevates the levels of early glycolytic intermediates.
he dysfunction at disease onset was accompanied by increased expression of the rate-limiting glycolytic enzyme phosphofructokinase-2 in activated astrocytes, and by selective reduction in spinal mitochondrial complex I activity
SGK3 is not required for insulin-induced PFK-2 activation and that this effect is likely mediated by PKBalpha.
Our results demonstrate that in diet-induced obesity, high Fru-2,6-P2 levels in transgenic livers caused changes in hepatic gene expression profiles for key gluconeogenic and lipogenic enzymes.
mouse islets expressed PFKFB2 at the mRNA level; PFK-2/FBPase-2 protein rather than its product fructose 2,6-P(2) is the over-riding determinant of glucose-induced insulin secretion through regulation of glucokinase activity or subcellular targeting.

Cow (Bovine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Interaktionspartner

Crystal structure of human and cattle heart PFKFB2 and the inhibitory influence of citrate on substrate binding has been described.
SGK3 is not required for insulin-induced PFK-2 activation and that this effect is likely mediated by PKBalpha.

PFKFB2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a (pfkfb2a) Antikörper
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2) Antikörper
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (pfkfb2) Antikörper
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Pfkfb2) Antikörper

4930568D07Rik Antikörper
PFK-2/FBPase-2 Antikörper
pfkfb2 Antikörper
RH2K Antikörper
zgc:56282 Antikörper

Bezeichner auf Proteinebene für PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 , pfk-2/fbpase-2 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-like , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 , 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme , 6PF-2-K/Fru-2,6-P2ase 2 , PFK/FBPase 2 , PFKFB, cardiac , fructose-2,6-bisphosphatase, cardiac isozyme , 6PF-2-K/Fru-2,6-P2ase heart-type isozyme , PFK-2/FBPase-2 gene B , 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart) , PFK-2/FBPase-2 , fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase , 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase

GENE ID	SPEZIES
393983	Danio rerio
457687	Pan troglodytes
693509	Macaca mulatta
100020159	Monodelphis domestica
100051146	Equus caballus
100170160	Xenopus (Silurana) tropicalis
100389023	Callithrix jacchus
100484471	Ailuropoda melanoleuca
100563872	Anolis carolinensis
100585652	Nomascus leucogenys
5208	Homo sapiens
18640	Mus musculus
24640	Rattus norvegicus
480011	Canis lupus familiaris
287019	Bos taurus
419850	Gallus gallus
100174086	Pongo abelii

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