PFKFB2 Produkte
(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
Kategorien
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte PFKFB2 Kategorien
PFKFB2 Antikörper
High quality antibodies with extensive validation data.
PFKFB2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PFKFB2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PFKFB2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7142693
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN392769
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN6145483
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PFKFB2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380333
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene PFKFB2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314736
Menge
2 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314735
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3079907
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PFKFB2 Produkten
: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." in: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).: "Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10640-51, (2013) (PubMed).
: "Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells." in: BMC cancer, Vol. 10, pp. 638, (2010) (PubMed).
: "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24223-32, (2009) (PubMed).
: "A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells." in: The Biochemical journal, Vol. 411, Issue 1, pp. 41-51, (2008) (PubMed).
: "Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells." in: Oncogene, Vol. 21, Issue 55, pp. 8414-27, (2002) (PubMed).
: "Isolation of novel heart-specific genes using the BodyMap database." in: Genomics, Vol. 74, Issue 1, pp. 115-20, (2001) (PubMed).
Synonyme und alternative Namen zu PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a (pfkfb2a), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (pfkfb2), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Pfkfb2), 4930568D07Rik, PFK-2/FBPase-2, pfkfb2, RH2K, zgc:56282Bezeichner auf Proteinebene für PFKFB2
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- pfk-2/fbpase-2
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-like
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
- 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme
- 6PF-2-K/Fru-2,6-P2ase 2
- PFK/FBPase 2
- PFKFB, cardiac
- fructose-2,6-bisphosphatase, cardiac isozyme
- 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
- PFK-2/FBPase-2 gene B
- 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart)
- PFK-2/FBPase-2
- fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase
- 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase
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