PIDD Produkte
(P53-Induced Death Domain Protein (PIDD))
Kategorien
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010].
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Ausgewählte PIDD Kategorien
PIDD Antikörper
High quality antibodies with extensive validation data.
Empfohlene PIDD Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN7261141
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7193396
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN7237334
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PIDD ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6229101
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PIDD Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7578795
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PIDD Produkten
: "An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy." in: Nature cell biology, Vol. 21, Issue 2, pp. 203-213, (2019) (PubMed).: "Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes." in: Molecular cancer research : MCR, Vol. 13, Issue 2, pp. 250-62, (2015) (PubMed).
: "Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway." in: The EMBO journal, Vol. 26, Issue 1, pp. 197-208, (2007) (PubMed).
: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, (2006) (PubMed).
: "PIDD mediates NF-kappaB activation in response to DNA damage." in: Cell, Vol. 123, Issue 6, pp. 1079-92, (2005) (PubMed).
: "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 843-6, (2004) (PubMed).
Synonyme und alternative Namen zu PIDD
p53 induced death domain protein 1 (Pidd1), p53-induced death domain protein 1 (PIDD1), p53-induced death domain protein 1 (Pidd1), 1200011D09Rik, AU042446, LRDD, Lrdd, PiddBezeichner auf Proteinebene für PIDD
- leucine-rich repeat and death domain-containing protein
- p53 protein induced, with death domain
- p53-induced protein with a death domain
- leucine-rich repeats and death domain containing
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