Kinesin Heavy Chain Member 2A (KIF2A) (N-Term) Peptid
KIF2A
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN978956
Kurzübersicht für Kinesin Heavy Chain Member 2A (KIF2A) (N-Term) Peptid (ABIN978956)
Target
KIF2A
(Kinesin Heavy Chain Member 2A (KIF2A))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-KIF2A antibody (Catalog #: ARP33902_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))
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Hintergrund
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KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Alias Symbols: HK2, KIF2
Protein Interaction Partner: CLSTN1,KLC1,KLC2
Protein Size: 706 -
Molekulargewicht
- 80 kDa
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Gen-ID
- 3796
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NCBI Accession
- NM_004520, NP_004511
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UniProt
- O00139
Target
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