A synthetic peptide for use as a blocking control in assays to test for specificity of KIF2 A antibody, Alternative Names: KIF2A control peptide, KIF2A antibody Blocking Peptide, Anti-KIF2A Blocking Peptide, Kinesin Heavy Chain Member 2A Blocking Peptide, HK2 Blocking Peptide, KIF2 Blocking Peptide, KIF2A, KIFA-2, KIFA 2, KIFA-2 Blocking Peptide, KIFA 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
KIF2A
(Kinesin Heavy Chain Member 2A (KIF2A))
Synonyme
HK2 Peptide, KIF2 Peptide, C530030B14Rik Peptide, Kif2 Peptide, Kns2 Peptide, M-kinesin Peptide, kif2-a Peptide, fj55b02 Peptide, wu:fj55b02 Peptide, kinesin family member 2A Peptide, kinesin heavy chain member 2A L homeolog Peptide, kinesin heavy chain member 2A Peptide, zgc:103670 Peptide, Kinesin-2 Peptide, KIF2A Peptide, Kif2a Peptide, kif2a.L Peptide, zgc:103670 Peptide, GL50803_17333 Peptide, GL50803_16456 Peptide
Hintergrund
KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.