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Kinesin Heavy Chain Member 2A (KIF2A) Peptid

KIF2A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978957
  • Target Alle KIF2A Produkte
    KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-KIF2A antibody (Catalog #: ARP34033_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))
    Synonyme
    HK2 Peptide, KIF2 Peptide, C530030B14Rik Peptide, Kif2 Peptide, Kns2 Peptide, M-kinesin Peptide, kif2-a Peptide, fj55b02 Peptide, wu:fj55b02 Peptide, kinesin family member 2A Peptide, kinesin heavy chain member 2A L homeolog Peptide, kinesin heavy chain member 2A Peptide, zgc:103670 Peptide, Kinesin-2 Peptide, KIF2A Peptide, Kif2a Peptide, kif2a.L Peptide, zgc:103670 Peptide, GL50803_17333 Peptide, GL50803_16456 Peptide
    Hintergrund
    KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].

    Alias Symbols: HK2, KIF2

    Protein Interaction Partner: CLSTN1,KLC1,KLC2

    Protein Size: 706
    Molekulargewicht
    80 kDa
    Gen-ID
    3796
    NCBI Accession
    NM_004520, NP_004511
    UniProt
    O00139
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