Beta-secretase 1 (BACE1) (N-Term) Peptid
BACE1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN973702
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Beta-secretase 1 (BACE1) (N-Term) Peptid (ABIN973702)
Target
BACE1
(Beta-secretase 1 (BACE1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-BACE1 antibody (Catalog #: ARP46851_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Hintergrund
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ASP2, BACE, FLJ90568, HSPC104, KIAA1149
Protein Interaction Partner: ATP1B1,CMPK1,ITM2C,KHSRP,NCSTN,PDIA3,PSAP,RANBP9,APP,ATP1B1,BRI3,CMPK1,CSNK1D,FURIN,GGA2,ITM2C,KHSRP,LRP1,MMP2,NCSTN,PDIA3,PLSCR1,PSAP,PSEN1,RANBP9,SELPLG,NCSTN
Protein Size: 501 -
Molekulargewicht
- 51 kDa
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Gen-ID
- 23621
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NCBI Accession
- NM_012104, NP_036236
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UniProt
- P56817
Target
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