A synthetic peptide for use as a blocking control in assays to test for specificity of BACE1 antibody, Alternative Names: BACE1 control peptide, BACE1 antibody Blocking Peptide, Anti-BACE1 Blocking Peptide, Beta-Site App-Cleaving Enzyme 1 Blocking Peptide, ASP2 Blocking Peptide, BACE Blocking Peptide, FLJ90568 Blocking Peptide, HSPC104 Blocking Peptide, KIAA1149 Blocking Peptide, BACE1, BACE-1, BACE 1, BACE-1 Blocking Peptide, BACE 1 Blocking Peptide
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.