Beta-secretase 1 (BACE1) (Middle Region) Peptid
BACE1
Reaktivität: Maus
Wirt: Synthetic
BP, WB
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- Target Alle BACE1 Produkte
- BACE1 (Beta-secretase 1 (BACE1))
- Protein Region
- Middle Region
- Spezies
- Maus
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Bace1 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BACE1 (Beta-secretase 1 (BACE1))
- Synonyme
- ASP2 Peptide, BACE Peptide, HSPC104 Peptide, C76936 Peptide, Bace Peptide, MGC145931 Peptide, BACE1 Peptide, zgc:77409 Peptide, beta-secretase 1 Peptide, beta-site APP cleaving enzyme 1 Peptide, beta-site APP-cleaving enzyme 1 Peptide, BACE1 Peptide, Bace1 Peptide, bace1 Peptide
- Hintergrund
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Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Alias Symbols: C76936
Protein Size: 501 - Molekulargewicht
- 56 kDa
- Gen-ID
- 23821
- NCBI Accession
- NM_011792, NP_035922
- UniProt
- P56818
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