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Toll-Like Receptor 4 (TLR4) Peptid

TLR4 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN940355
  • Target Alle TLR4 Produkte
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    LGEFRNEGNL EKFDKSALEG LCNLTIEEFR LAYLDYYLDD IIDLFNCLTN
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of TLR4 antibody,
    Alternative Names: TLR4 control peptide, TLR4 antibody Blocking Peptide, Anti-TLR4 Blocking Peptide, toll-like receptor 4 Blocking Peptide, ARMD10 Blocking Peptide, CD284 Blocking Peptide, TOLL Blocking Peptide, hToll Blocking Peptide, TLR4, TLR-4, TLR 4, TLR-4 Blocking Peptide, TLR 4 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Synonyme
    ARMD10 Peptide, CD284 Peptide, TLR-4 Peptide, TOLL Peptide, Lps Peptide, Ly87 Peptide, Ran/M1 Peptide, Rasl2-8 Peptide, toll like receptor 4 Peptide, toll-like receptor 4 Peptide, TLR4 Peptide, Tlr4 Peptide
    Hintergrund
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain.
    Molekulargewicht
    93 kDa
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