MHC Class I Polypeptide-Related Sequence A (MICA) (Middle Region) Peptid
Kurzübersicht für MHC Class I Polypeptide-Related Sequence A (MICA) (Middle Region) Peptid (ABIN8105363)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- MICA Peptide - middle region
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Sequenz
- VQSGFLAEVH LDGQPFLRYD RQKCRAKPQG QWAEDVLGNK TWDRETRDLT
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-MICA Antibody (ARP44245_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Hintergrund
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Background Information: MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.
Alternative Symbols: MIC-A, PERB11.1
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Molekulargewicht
- 36kDa
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Gen-ID
- 100507436
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NCBI Accession
- NP_001170990
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UniProt
- Q96QC4
Target
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