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MHC Class I Polypeptide-Related Sequence A (MICA) (Middle Region) Peptid

MICA Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN2183541
  • Target Alle MICA Produkte
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    VQSGFLAEVH LDGQPFLRYD RQKCRAKPQG QWAEDVLGNK TWDRETRDLT
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-MICA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Synonyme
    MIC-A Peptide, PERB11.1 Peptide, MHC class I polypeptide-related sequence A Peptide, MICA Peptide
    Hintergrund
    MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.

    Alias Symbols: MIC-A, PERB11.1

    Protein Size: 332
    Molekulargewicht
    36 kDa
    Gen-ID
    100507436
    NCBI Accession
    NM_001177519, NP_001170990
    UniProt
    Q96QC4
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