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Galanin (GAL) Peptid

GAL Reaktivität: Maus Wirt: Synthetic BP, Func
Produktnummer ABIN7582103
  • Target Alle Galanin (GAL) Produkte
    Galanin (GAL)
    Protein-Typ
    Synthetic
    Spezies
    Maus
    Quelle
    • 14
    Synthetic
    Applikation
    Blocking Peptide (BP), Functional Studies (Func)
    Verwendungszweck
    A Non-Selective, Potent Galanin Receptor Agonist
    Sequenz
    GWTLNSAGYL LGPHAIDNHR SFSDKHGLT-NH2
    Spezifität
    Toxin target: Galanin receptors, Thr29 - C-terminal amidation
    Produktmerkmale
    A Non-Selective, Potent Galanin Receptor Agonist
    Reinheit
    ≥98 % (HPLC)
  • Applikationshinweise
    Antigen Preadsorption Control: 1 - 10 nM
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 μM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
    Buffer
    Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.,The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.
  • Target
    Galanin (GAL)
    Hintergrund
    Galanin is a peptide hormone that acts as a non-selective and potent galanin receptor agonist. Galanin is a C-terminally amidated 29-residue peptide (30 in humans). It was first isolated from porcine intestine1,2.Galanin is widely distributed throughout the central and peripheral nervous systems and its biological activity includes contraction or relaxation of gut smooth muscles, inhibition of insulin and somatostatin release, and modulation of hormone secretion from the pituitary and adrenal gland. It is believed that galanin plays an important role as a neuromodulator of endocrine secretion and synaptic transmission1.Galanin receptors belong to the family of G-protein coupled receptors and consist of three subtypes: GalR1, GalR2, and GalR3. Additional studies show that galanin and its receptors are involved in the transmission and modulation of nociception2.
    Molekulargewicht
    3164 Da
    UniProt
    P10683
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