PD-L1 Proteine
(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
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PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Cynomolgus, Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
HPLC verified
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>98 % as determined by SDS-PAGE.
Active
6 Referenzen
PD-L1
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Cynomolgus, Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
2 Referenzen
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
3 Referenzen
PD-L1
Spezies: Human
Wirt: HEK-293T Cells
Recombinant
SDS, WB, ELISA, PI
2 Abbildungen
PD-L1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
1 reference
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
PD-L1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
PD-L1
Spezies: Ratte
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
Aktuelle Publikationen für unsere PD-L1 Proteine
: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).
: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).
: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." in: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).
: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." in: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).
: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).
: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." in: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).
: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).
Aliase für PD-L1 Proteine
CD274 molecule (CD274) ProteineCD274 antigen (Cd274) Proteine
programmed cell death 1 ligand 2 (PDCD1LG2) Proteine
CD274 molecule (Cd274) Proteine
A530045L16Rik Proteine
B7-H Proteine
B7H1 Proteine
B7h1 Proteine
PD-L1 Proteine
PDCD1L1 Proteine
Pdcd1l1 Proteine
PDCD1LG1 Proteine
Pdcd1lg1 Proteine
PDL1 Proteine
Pdl1 Proteine
RGD1566211 Proteine
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- PDCD5 Proteine
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- PDE1C Proteine
- PDE2A Proteine
- PDE3A Proteine
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- PDE4C Proteine
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