anti-SERPINB5 (SERPINB5) Antikörper

Bezeichnung:: anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 Antikörper (SERPINB5)

Auf www.antikoerper-online.de finden Sie aktuell 145 serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SERPINB5 Kits (26) und SERPINB5 Proteine (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 206 SERPINB5 Produkte verfügbar.

Synonyme:: 1110036M19Rik, AI462524, AI646751, maspin, ovalbumin, PI-5, Pi5, Spi7

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	SERPINB5	20724	P70124
	SERPINB5	5268	P36952
	SERPINB5	116589	P70564
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-SERPINB5 (SERPINB5) Antikörper

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anti-Mouse (Murine) SERPINB5 Antikörper:

anti-Human SERPINB5 Antikörper:

anti-Rat (Rattus) SERPINB5 Antikörper:

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Verknüpfte Pathways mit anti-SERPINB5 Antikörper

p53 Signalweg

Weitere Produktkategorien zu SERPINB5 Antikörper

Am meisten referenzierte anti-SERPINB5 Antikörper

Human Monoclonal SERPINB5 Primary Antibody für WB - ABIN967456 : Hopkins, Whisstock: Function of maspin. in Science (New York, N.Y.) 1994 (PubMed)
Show all 3 Pubmed References
Cow (Bovine) Polyclonal SERPINB5 Primary Antibody für IHC, WB - ABIN2777125 : Vereecken, Reynaert, Lalmand, Zouaoui-Boudjeltia, Heenen, Van Den Heule, Petein: Decreased immunoreactive maspin expression in intermediate thickness and thick primary melanoma lesions. in The Journal of international medical research 2006 (PubMed)
Show all 4 Pubmed References
Human Polyclonal SERPINB5 Primary Antibody für IF (p), IHC (p) - ABIN728233 : Sun, Wu, Ruan, Zheng, Song, Zhun, Wu, Gotlieb: Expression patterns of maspin and mutant p53 are associated with the development of gestational trophoblastic neoplasia. in Oncology letters 2016 (PubMed)
Human Polyclonal SERPINB5 Primary Antibody für IF, IHC (p) - ABIN656020 : Kim, Jang, Kim, Park, Chang, Lee, Lee, Heo, Choi, Choi, Rhee, Lee: Aberrant maspin expression is involved in early carcinogenesis of gallbladder cancer. in Tumour biology 2010 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen SERPINB5 Interaktionspartner

Mouse (Murine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Interaktionspartner

maspin is a powerful context-dependent tumor suppressor.
these data indicate that SerpinB5 expression and phosphorylation are developmentally regulated. In vitro analyses indicate that SerpinB5 phosphorylation is regulated by EGFR (zeige EGFR Antikörper) ligands, but EGF (zeige EGF Antikörper) appears to be the only able to induce SerpinB5 nuclear localization.
perturbation of genes near maspin may in fact explain poor survival in certain patient cohorts with low maspin expression
evidence demonstrates that D(346) is a critical cis (zeige CISH Antikörper)-element in maspin sequence that determines the molecular context and subcellular localization of maspin.
a novel mechanism by which maspin utilizes its cysteine thiols to inhibit oxidative stress and cell growth.
results suggest that maspin, a tumor suppressor, may play an important role in embryo implantation
The nuclear localization of maspin is required for its tumor and metastasis suppressor functions in vivo.
SERPINB5 and AKAP12 (zeige AKAP12 Antikörper) may have a role in increased metastasis in pancreatic ductal adenocarcinoma
PAR-1 (zeige MARK2 Antikörper) negatively regulates the expression of the Maspin tumor-suppressor gene in the acquisition of the metastatic melanoma phenotype
Results describe a mechanism by which maspin exerts its effect on endothelial cell adhesion and migration through an integrin signal transduction pathway.

Human serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Interaktionspartner

SNPs affected SERPINB5 expression and protein stability, which significantly correlated with tumour expression and subsequently with tumour development and aggressiveness. Taken together, our findings regarding these biomarkers provide a prediction model for risk assessment.
Maspin is spontaneously secreted as an exosomal protein to regulate tumor/stromal interactions.
Study results provide new insights into the molecular mechanisms of maspin suppression in response to HBx, and revealed nuclear IKKalpha (zeige CHUK Antikörper) as a prognostic biomarker and a potential therapeutic target to improve the clinical outcome of HBV-associated HCC (zeige FAM126A Antikörper) patients.
Mechanistic investigations found that quercetin suppressed Snail (zeige SNAI1 Antikörper)-dependent Akt (zeige AKT1 Antikörper) activation by upregulating maspin and Snail (zeige SNAI1 Antikörper)-independent a disintegrin and metalloproteinase (ADAM) 9 (zeige ADAM9 Antikörper) expression pathways to modulate the invasive ability of NSCLC cells.
High HDAC1 (zeige HDAC1 Antikörper) expression may contribute to the aggressiveness of human breast cancer with cytoplasmic-only expression of maspin
These results reveal a novel biological function of Maspin in modulating macrophage activity
Heterozygous TC of the SERPINB5 rs17071138 polymorphism may be a factor that increases susceptibility to oral cancer.
Impact of Maspin Polymorphism rs2289520 G/C and Its Interaction with Gene to Gene, Alcohol Consumption Increase Susceptibility to Oral Cancer Occurrence
Cytoplasmic expression of maspin could be an independent unfavourable prognostic indicator in patients with lung squamous cell carcinoma (SCC (zeige CYP11A1 Antikörper)).
Results demonstrated that Maspin suppressed growth, proliferation and invasion by delaying cell cycle transition and promoting apoptosis in cutaneous squamous cell carcinoma cells.

SERPINB5 Antigen-Profil

Beschreibung des Gens

may act as a tumor suppressor

Alternative names and synonyms associated with SERPINB5

serine (or cysteine) peptidase inhibitor, clade B, member 5 (Serpinb5) Antikörper
serpin family B member 5 (SERPINB5) Antikörper
serpin family B member 5 (Serpinb5) Antikörper
serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog (serpinb5.S) Antikörper

1110036M19Rik Antikörper
AI462524 Antikörper
AI646751 Antikörper
maspin Antikörper
ovalbumin Antikörper
PI-5 Antikörper
Pi5 Antikörper
Spi7 Antikörper

Bezeichner auf Proteinebene für SERPINB5

peptidase inhibitor 5 , protease inhibitor 5 , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 , serine (or cysteine) proteinase inhibitor, clade B, member 5 , serine protease inhibitor 7 , serpin B5 , PI-5 , protease inhibitor 5 (maspin) , serine (or cysteine) peptidase inhibitor, clade B, member 5

GENE ID	SPEZIES
20724	Mus musculus
5268	Homo sapiens
116589	Rattus norvegicus
444699	Xenopus laevis
420900	Gallus gallus
476177	Canis lupus familiaris
534323	Bos taurus

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Show all anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Antikörper with Pubmed References

Mouse (Murine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Interaktionspartner

Human serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with SERPINB5

Bezeichner auf Proteinebene für SERPINB5