Osteoactivin Proteine
(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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GPNMB
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
GPNMB
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
GPNMB
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS
1 image
GPNMB
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
GPNMB
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % by SDS-PAGE.
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
GPNMB
Spezies: Human
Wirt: Mammalian Cells
Recombinant
SDS, WB, ELISA
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 98 % as determined by reducing SDS-PAGE.
GPNMB
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aktuelle Publikationen für unsere Osteoactivin Proteine
: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." in: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
Aliase für Osteoactivin Proteine
glycoprotein nmb (Gpnmb) Proteineglycoprotein nmb (GPNMB) Proteine
glycoprotein (transmembrane) nmb (Gpnmb) Proteine
glycoprotein nmb L homeolog (gpnmb.L) Proteine
DC-HIL Proteine
Dchil Proteine
HGFIN Proteine
ipd Proteine
NMB Proteine
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