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ORAI1 Produkte

(ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Kategorien

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011].

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Ausgewählte ORAI1 Kategorien

ORAI1 Antikörper

High quality antibodies with extensive validation data.

ORAI1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene ORAI1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation WB, IHC, IF, FACS, LCI, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7043408
Menge 25 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p)
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN541622
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7146306
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ORAI1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1124741
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1124740
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1124739
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ORAI1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3125369
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3117264
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ORAI1 Produkten

Domínguez-Rodríguez, Mayoral-Gonzalez, Avila-Medina, de Rojas-de Pedro, Calderón-Sánchez, Díaz, Hmadcha, Castellano, Rosado, Benitah, Gomez, Ordoñez, Smani: "Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion." in: Frontiers in physiology, Vol. 9, pp. 813, (2018) (PubMed).

Ávila-Medina, Calderón-Sánchez, González-Rodríguez, Monje-Quiroga, Rosado, Castellano, Ordóñez, Smani: "Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells." in: The Journal of biological chemistry, Vol. 291, Issue 40, pp. 21148-21159, (2016) (PubMed).

Samanta, Kar, Mirams, Parekh: "Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression." in: Cell reports, Vol. 12, Issue 2, pp. 203-16, (2015) (PubMed).

Lee, Veatch, Baird, Holowka: "Molecular mechanisms of spontaneous and directed mast cell motility." in: Journal of leukocyte biology, Vol. 92, Issue 5, pp. 1029-41, (2012) (PubMed).

Kar, Nelson, Parekh: "Selective activation of the transcription factor NFAT1 by calcium microdomains near Ca2+ release-activated Ca2+ (CRAC) channels." in: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 14795-803, (2011) (PubMed).

Krapivinsky, Krapivinsky, Stotz, Manasian, Clapham: "POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 48, pp. 19234-9, (2011) (PubMed).

Burns, Schmidt, Williams, Kim, Girirajan, Elsea: "Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome." in: Human molecular genetics, Vol. 19, Issue 20, pp. 4026-42, (2010) (PubMed).

Martin, Willoughby, Ciruela, Ayling, Pagano, Wachten, Tengholm, Cooper: "Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8." in: Molecular pharmacology, Vol. 75, Issue 4, pp. 830-42, (2009) (PubMed).

Smyth, Petranka, Boyles, DeHaven, Fukushima, Johnson, Williams, Putney: "Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis." in: Nature cell biology, Vol. 11, Issue 12, pp. 1465-72, (2009) (PubMed).

Potier, Gonzalez, Motiani, Abdullaev, Bisaillon, Singer, Trebak: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).

Synonyme und alternative Namen zu ORAI1

ORAI calcium release-activated calcium modulator 1 (ORAI1), ORAI calcium release-activated calcium modulator 1 (Orai1), ORAI calcium release-activated calcium modulator 1b (orai1b), ORAI calcium release-activated calcium modulator 1 S homeolog (orai1.S), ORAI calcium release-activated calcium modulator 1 (orai1), CRACM1, D730049H07Rik, im:7146264, LOC100218031, orai-1, orai1, ORAI1, orai2, ORAT1, RGD1311873, TMEM142A, Tmem142a, tmem142a, zgc:109721

Bezeichner auf Proteinebene für ORAI1

  • calcium release-activated calcium channel protein 1
  • calcium release-activated calcium modulator 1
  • protein orai-1
  • transmembrane protein 142A
  • calcium release-activated calcium channel 1
  • ORAI calcium release-activated calcium modulator 1
  • protein orai-2
  • transmembrane protein 142B
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