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ORC2 Produkte

(Origin Recognition Complex Subunit 2 (ORC2))
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010].

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Ausgewählte ORC2 Kategorien

ORC2 Antikörper

High quality antibodies with extensive validation data.

ORC2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ORC2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ORC2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN562076
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN2855601
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN108579
Menge 50 μL
Datenblatt Datenblatt

Empfohlene ORC2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1146513
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1146514
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1146515
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ORC2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313650
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3094298
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3122769
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ORC2 Produkten

Murai, Tang, Leo, Baechler, Redon, Zhang, Al Abo, Rajapakse, Nakamura, Jenkins, Aladjem, Pommier: "SLFN11 Blocks Stressed Replication Forks Independently of ATR." in: Molecular cell, Vol. 69, Issue 3, pp. 371-384.e6, (2019) (PubMed).

Ehlén, Nodin, Rexhepaj, Brändstedt, Uhlén, Alvarado-Kristensson, Pontén, Brennan, Jirström: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." in: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).

Song, Levin, Varkey, Post, Bermudez, Hurwitz, Tomkinson: "A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22721-30, (2007) (PubMed).

Quintana, Hou, Thome, Hendricks, Saha, Dutta: "Identification of HsORC4, a member of the human origin of replication recognition complex." in: The Journal of biological chemistry, Vol. 272, Issue 45, pp. 28247-51, (1997) (PubMed).

Takahara, Bong, Brevard, Eddy, Haley, Sait, Shows, Hoffman, Greenspan: "Mouse and human homologues of the yeast origin of replication recognition complex subunit ORC2 and chromosomal localization of the cognate human gene ORC2L." in: Genomics, Vol. 31, Issue 1, pp. 119-22, (1996) (PubMed).

Synonyme und alternative Namen zu ORC2

Origin recognition complex subunit 2 (Orc2), origin recognition complex second largest subunit 2 (ORC2), origin recognition complex subunit 2 (ORC2), origin recognition complex, subunit 2 (Orc2), origin recognition complex subunit 2 S homeolog (orc2.S), Origin recognition complex subunit 2 (orc-2), ATORC2, AU041563, CG3041, Dmel\\CG3041, DmORC 2, DmORC2, DmOrc2, DmOrc2p, F13M22.6, F13M22_6, fs(3)293, fs(3)293-19, k43, l(3)88Ab, l(3)A5, l(3)dsl5, l(3)K43, l(3)k43, l(3)SG44, ORC, Orc-2, ORC2, orc2, orc2-a, ORC2L, Orc2l, orc2l, Orc2p, ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2, origin recognition complex second largest subunit 2, rDmORC, xorc2

Bezeichner auf Proteinebene für ORC2

  • CG3041-PA
  • Orc2-PA
  • lethal(3)88Ab
  • origin recognition complex
  • origin recognition complex subunit 2
  • origin recognition complex protein 2 homolog
  • origin recognition complex, subunit 2 homolog
  • origin recognition complex, subunit 2-like
  • origin recognition complex subunit 2 homolog
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