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OAS1 Proteine

(2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

12 Treffer

custom-made OAS1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7554812
 
OAS1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Produktnummer ABIN1313295
 
OAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Produktnummer ABIN7121603
 
OAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7578592
 
OAS1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Produktnummer ABIN7396667
 
OAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Produktnummer ABIN7396664
 
OAS1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7396670
 
OAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Produktnummer ABIN2130923
 
custom-made OAS1 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
Produktnummer ABIN3094284
 
OAS1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2727845
 
OAS1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant WB, SDS
Produktnummer ABIN6120718
 
OAS1 Spezies: Schwein Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1622221
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Pig
    • Rat
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 1-400
    • AA 1-349
    • AA 1-364
    • AA 139-358
    • AA 74-165
    • Transcript Variant 2
  • Konjugat
    • His tag
    • GST tag
    • Unkonjugiert
    • Myc-DYKDDDDK Tag
    • Strep Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online
    • Abbexa
    • CUSABIO
    • OriGene

Aktuelle Publikationen für unsere OAS1 Proteine

Yin, Zhou, Dai: "The association of elevated 2',5'-oligoadenylate-dependent RNase L with lung cancer correlated with deficient enzymatic activity and decreased capacity of RNase L dimerization." in: Lung cancer (Amsterdam, Netherlands), Vol. 78, Issue 1, pp. 30-8, (2012) (PubMed).

Aliase für OAS1 Proteine

2',5'-oligoadenylate synthetase 1 (OAS1) Proteine
2'-5'-oligoadenylate synthetase 1 (OAS1) Proteine
2'-5' oligoadenylate synthetase 1A (Oas1a) Proteine
protein phosphatase 2 catalytic subunit beta (Ppp2cb) Proteine
2'-5'-oligoadenylate synthetase 1 (Oas1) Proteine
IFI-4 Proteine
L3 Proteine
OAS1 Proteine
OIAS Proteine
OIASI Proteine
Pp2a2 Proteine
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