anti-NR2E3 (NR2E3) Antikörper

Bezeichnung:: anti-Nuclear Receptor Subfamily 2, Group E, Member 3 Antikörper (NR2E3)

Auf www.antikoerper-online.de finden Sie aktuell 105 Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NR2E3 Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 119 NR2E3 Produkte verfügbar.

Synonyme:: A930035N01Rik, ESCS, LOC100228348, PNR, rd7, RNR, RP37, wu:fj55b07, zgc:103631

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	NR2E3	10002	Q9Y5X4
	NR2E3	23958	Q9QXZ7
	NR2E3	100365683
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human NR2E3 Antikörper:

anti-Mouse (Murine) NR2E3 Antikörper:

anti-Rat (Rattus) NR2E3 Antikörper:

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Verknüpfte Pathways mit anti-NR2E3 Antikörper

Weitere Produktkategorien zu NR2E3 Antikörper

Am meisten referenzierte anti-NR2E3 Antikörper

Human Polyclonal NR2E3 Primary Antibody für WB - ABIN523375 : Qin, Knapinska, Dobri, Madoux, Chase, Hodder, Petrukhin: In pursuit of synthetic modulators for the orphan retina-specific nuclear receptor NR2E3. in Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2013 (PubMed)
Cow (Bovine) Polyclonal NR2E3 Primary Antibody für WB - ABIN2780915 : Hayashi, Gekka, Goto-Omoto, Takeuchi, Kubo, Kitahara: Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity. in Ophthalmology 2005 (PubMed)

Weitere Antikörper gegen NR2E3 Interaktionspartner

Human Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3) Interaktionspartner

A substitution in exon 2 of NR2E3, expressed the expected pluripotency markers, displayed in vivo differentiation potential to the three germ layers and had normal karyotype
Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1 (zeige NR2E1 Antikörper)) are human orthologs of the NR2E group.
The frameshift mutation found in patient 1, p.I307LfsX33, is a new causative mutation for ESCS; it is located in exon 6. This mutation truncates the 410 amino acids in the normal NR2E3 protein into 306 amino acids and causes the synthesis of a protein lacking more than half of the ligand-binding domain.
Autosomal dominant retinitis pigmentosa due to p.Gly56Arg mutation in the NR2E3 gene
NR2E3 is a novel epigenetic regulator that helps to maintain a normal epigenetic status in response to benzo(a)pyrene mediated toxic injury. NR2E3 may be a potential target for cancer prevention.
Study presents evidence that PNR could promote ERalpha (zeige ESR1 Antikörper)-negative breast cancer metastasis through activation of IL-13Ralpha2-mediated signaling pathway.
Direct sequencing of NR2E3 identified 3 previously described mutations and 4 novel mutations in Enhanced S-cone syndrome (ESCS) forms
Molecular genetic studies helped to identify a novel p.D406G mutation in NR2E3 of the Goldmann-Favre syndrome (GFS) and vasoproliferative tumors of the retina affected members.
Genetic screening confirmed the presence of two disease-causing mutations in the NR2E3 gene in each study patient, as well as identified a novel mutation (202 A > G, S68G).
PNR/NR2E3 and related NRs (zeige SPNS1 Antikörper) such as TLX (zeige CD46 Antikörper) and COUPTFs can selectively associate with the developmental corepressor BCL11A (zeige BCL11A Antikörper) via a conserved motif F/YSXXLXXL/Y within the RID1 domain.

Mouse (Murine) Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3) Interaktionspartner

Chemical compounds identified as modulators of Nr2e3 activity may be useful for the treatment of RP through their effects on expression of disease-causing mutant genes.
NR2E3 is a novel epigenetic regulator that helps to maintain a normal epigenetic status in response to benzo(a)pyrene mediated toxic injury. NR2E3 may be a potential target for cancer prevention.
Study presents evidence that PNR could promote ERalpha (zeige ESR1 Antikörper)-negative breast cancer metastasis through activation of IL-13Ralpha2-mediated signaling pathway.
Modifier genes as therapeutics: the nuclear hormone receptor (zeige NR0B1 Antikörper) Rev Erb alpha (Nr1d1 (zeige NR1D1 Antikörper)) rescues Nr2e3 associated retinal disease.
PNR/NR2E3 and related NRs (zeige SPNS1 Antikörper) such as TLX (zeige NR2E1 Antikörper) and COUPTFs can selectively associate with the developmental corepressor BCL11A (zeige BCL11A Antikörper) via a conserved motif F/YSXXLXXL/Y within the RID1 and RID2 domains.
These studies further support the 'transcriptional dominance' model of photoreceptor cell fate determination and provide insights into the pathogenesis of retinal disease phenotypes caused by NR2E3 mutations.
These studies reveal a novel role for Nr1d1 (zeige NR1D1 Antikörper), in conjunction with its cofactor Nr2e3, in regulating transcriptional networks critical for photoreceptor development and function.
These experiments show that in mature vertebrate retina Nr2e3 is expressed exclusively in rods and that Nr2e3 functions as a repressor of cone-specific genes in rod photoreceptor cells.
Our studies reveal a critical role of NR2E3 in establishing functional specificity of NRL (zeige NRL Antikörper)-expressing photoreceptor precursors during retinal neurogenesis.
NR2E3 acts simultaneously in different cell types: in late mitotic progenitors, newly differentiating post mitotic cells, and mature rods and cones.

Zebrafish Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3) Interaktionspartner

The developmental expression profile of zebrafish nr2e1 (zeige NR2E1 Antikörper) and nr2e3 is consistent with evolutionary conserved functions in eye and rostral brain structures.

NR2E3 Antigen-Profil

Beschreibung des Gens

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with NR2E3

nuclear receptor subfamily 2 group E member 3 (NR2E3) Antikörper
nuclear receptor subfamily 2, group E, member 3 (Nr2e3) Antikörper
nuclear receptor subfamily 2, group E, member 3 (nr2e3) Antikörper
nuclear receptor subfamily 2 group E member 3 (Nr2e3) Antikörper

A930035N01Rik Antikörper
ESCS Antikörper
LOC100228348 Antikörper
PNR Antikörper
rd7 Antikörper
RNR Antikörper
RP37 Antikörper
wu:fj55b07 Antikörper
zgc:103631 Antikörper

Bezeichner auf Proteinebene für NR2E3

photoreceptor-specific nuclear receptor , retina-specific nuclear receptor , nuclear receptor subfamily 2, group E, member 3 , retinal degeneration 7 , nuclear receptor subfamily 2 group E member 3 , LOW QUALITY PROTEIN: photoreceptor-specific nuclear receptor , NR2D2 , PNR , fj55b07

GENE ID	SPEZIES
10002	Homo sapiens
100228348	Taeniopygia guttata
23958	Mus musculus
281944	Bos taurus
100365683	Rattus norvegicus
492496	Danio rerio
100714986	Cavia porcellus

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