NR2E3 Antikörper (AA 1-100)

Produktnummer ABIN1385816

Produktdetails anti-NR2E3 Antikörper

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2E3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NR2E3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NR2E3

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Andere Bezeichnung: NR2E3 (NR2E3 Produkte)

Synonyme: ESCS antikoerper, PNR antikoerper, RNR antikoerper, RP37 antikoerper, rd7 antikoerper, LOC100228348 antikoerper, A930035N01Rik antikoerper, wu:fj55b07 antikoerper, zgc:103631 antikoerper, nuclear receptor subfamily 2 group E member 3 antikoerper, nuclear receptor subfamily 2, group E, member 3 antikoerper, NR2E3 antikoerper, Nr2e3 antikoerper, nr2e3 antikoerper

Hintergrund:

Synonyms: ESCS, ESCS, NR2 E3, Nr2e3, NR2E3_HUMAN, Nuclear receptor subfamily 2 group E member 3, Photoreceptor specic nuclear receptor, Photoreceptor-specic nuclear receptor antibody PNR, Rd 7, rd7, Retina specic nuclear receptor, Retina-specic nuclear receptor, Retinal degeneration 7, Retinal degeneration 7, RNR, RP37.

Background: Photoreceptor-specific nuclear receptor, also known as NR2E3 or PNR, belongs to a large family of nuclear hormone receptor transcription factors. The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding. NR2E3 has a role in regulating the signaling pathway elemental to the photoreceptor cell function and in regulating pathways involved in embryonic development. NR2E3 is an eye specific nuclear protein found in the outer nuclear layer of the adult retina (where the nuclei of cone and rod photoreceptors are located). Defects in this gene encoding for the protein, which localizes to chromosome 15q22.32, cause enhanced S cone syndrome.

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway