NHEJ1 Produkte
(Nonhomologous End-Joining Factor 1 (NHEJ1))
Kategorien
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008].
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Ausgewählte NHEJ1 Kategorien
NHEJ1 Antikörper
High quality antibodies with extensive validation data.
NHEJ1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NHEJ1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NHEJ1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Monkey
Applikation
WB, IF, IHC, FACS, IHC (p)
Validierungen
- (15)
Kat. Nr.
ABIN1499728
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IF, IHC
Validierungen
- (5)
Kat. Nr.
ABIN7261171
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN2857060
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NHEJ1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1145258
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1145259
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1145260
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NHEJ1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124193
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312543
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3084605
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NHEJ1 Produkten
: "PHF6 promotes non-homologous end joining and G2 checkpoint recovery." in: EMBO reports, Vol. 21, Issue 1, pp. e48460, (2020) (PubMed).: "XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining." in: Nature structural & molecular biology, Vol. 25, Issue 10, pp. 971-980, (2018) (PubMed).
: "PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF." in: Cell reports, Vol. 17, Issue 2, pp. 541-555, (2016) (PubMed).
: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).
: "C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin." in: Biochemical and biophysical research communications, Vol. 439, Issue 2, pp. 173-8, (2013) (PubMed).
: "Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype." in: Human mutation, Vol. 31, Issue 9, pp. 1059-68, (2010) (PubMed).
: "Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 11, pp. 4518-23, (2007) (PubMed).
: "Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 31937-43, (2007) (PubMed).
: "XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining." in: Cell, Vol. 124, Issue 2, pp. 301-13, (2006) (PubMed).
Synonyme und alternative Namen zu NHEJ1
non-homologous end joining factor 1 (NHEJ1), non-homologous end joining factor 1 S homeolog (nhej1.S), non-homologous end joining factor 1 (nhej1), solute carrier family 23 member 3 (SLC23A3), nonhomologous end-joining factor 1 (nhej1), nonhomologous end-joining factor 1 (Nhej1), 1700029B21Rik, cernunnos, NHEJ1, XLF, zgc:85657Bezeichner auf Proteinebene für NHEJ1
- nonhomologous end-joining factor 1
- non-homologous end-joining factor 1
- XRCC4-like factor
- protein cernunnos
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