anti-MAP3K7 (MAP3K7) Antikörper

Bezeichnung:: anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 Antikörper (MAP3K7)

Auf www.antikoerper-online.de finden Sie aktuell 178 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K7 Proteine (7) und MAP3K7 Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 211 MAP3K7 Produkte verfügbar.

Synonyme:: B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	MAP3K7	313121	P0C8E4
	MAP3K7	6885	O43318
	MAP3K7	26409	Q62073
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Weitere Antikörper gegen MAP3K7 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Interaktionspartner

miR (zeige MLXIP Antikörper)-146a, serving as a tumor suppressor, may significantly promote GC cell apoptosis by inhibition of the NF-kappaB (zeige NFKB1 Antikörper) signaling pathway via targeting TAK1.
In conclusion, for the first time, we report that TRADD (zeige TRADD Antikörper), TRAF2 (zeige TRAF2 Antikörper), RIP1 (zeige UQCRFS1 Antikörper) and TAK1 play a role in the regulating TNF-alpha (zeige TNF Antikörper) signalling in human myometrium. These findings are of significance given the central role of TNF-alpha (zeige TNF Antikörper) in the processes of human labour and delivery.
Rab1 (zeige RAB1A Antikörper) is regulated by the host in a similar fashion, and that the innate immunity kinase TAK1 and Legionella effectors compete to regulate Rab1 (zeige RAB1A Antikörper) by switch II modifications during infection.
nMet accelerated HCC (zeige FAM126A Antikörper) tumorigenesis and metastasis via the activation of TAK1/NF-kappaB (zeige NFKB1 Antikörper) pathway.
TAK1 protein expression increased in cartilage tissue from spinal tuberculosis patients.
TAK1 regulates Nrf2 (zeige GABPA Antikörper) through modulation of Keap-p62/SQSTM1 (zeige SQSTM1 Antikörper) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.
Overexpression of TAK1 was strongly associated with positive lymph node metastasis in pancreatic ductal adenocarcinoma.
dysregulation of the TAK1 complex produces a close phenocopy of Frontometaphyseal Dysplasia caused by FLNA (zeige FLNA Antikörper) mutations; furthermore, the pathogenesis of some of the filaminopathies caused by FLNA (zeige FLNA Antikörper) mutations might be mediated by misregulation of signaling coordinated through the TAK1 signaling complex
although TAK1 is located at the crossroad of inflammation, immunity, and cancer, this study reports MAP3K7 mutations in a developmental disorder affecting mainly cartilage, bone, and heart
This study suggests that aberrant activity of TAK1 impairs autophagy and subsequently leads to alterations in the vitality of retinal pigment epithelial cells.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Interaktionspartner

The conversion of Tak1 (zeige NR2C2 Antikörper)-B to Tak1 (zeige NR2C2 Antikörper)-A consistently led to significant accumulation of lipids in cultured AML12cells, as well as the dysregulation of several lipid metabolism-related genes in mouse liver. Different functional properties of the two isoforms may explain the conflicting functions previously reported for Tak1 (zeige NR2C2 Antikörper).
demonstrate the efficiency of ad--siRNA-TAK1 (zeige NR2C2 Antikörper) in controlling joint inflammation of Collagen-Induced Arthritis, which is associated with the suppression of the expression of pro-inflammatory cytokines and JNK (zeige MAPK8 Antikörper) activation.
These data, in addition to the fact that Map3k7 is upregulated in the sinus venous-the source of cells for the SAN-suggest that Map3k7 may be an endogenous regulator of the SAN fate
These results present a novel in vivo function, the negative role of TAK1 (zeige NR2C2 Antikörper) in marginal zone B-cell development that is likely associated with NF-kappaB2 activation.
Tnfr1 (zeige TNFRSF1A Antikörper) deletion partially restored thymic and lung macrophages.
TAK1 (zeige NR2C2 Antikörper) is required for PPARgamma (zeige PPARG Antikörper) transactivation and promotes PPARgamma (zeige PPARG Antikörper) transcriptional activity synergistically with TAK1 binding protein 1 (TAB1 (zeige TAB1 Antikörper)).
inhibition of TAK1 (zeige NR2C2 Antikörper) triggered two caspase 8 (zeige CASP8 Antikörper) activation pathways through the induction of RIP1 (zeige RALBP1 Antikörper)-FADD (zeige FADD Antikörper)-caspase 8 (zeige CASP8 Antikörper) complex as well as FLIP cleavage/degradation.
Transforming growth factor-beta activated kinase 1 (TAK1) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) development.
TAK1 (zeige NR2C2 Antikörper) regulates Nrf2 (zeige NFE2L2 Antikörper) through modulation of Keap-p62/SQSTM1 (zeige SQSTM1 Antikörper) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.
Mekk1 (zeige MAP2K1 Antikörper) (encoded by Map3k1 (zeige MAP3K1 Antikörper)) signaling activates Mapks to regulate Cdkn1b (zeige CDKN1B Antikörper) (encoding p27(Kip1 (zeige CDKN1B Antikörper))) expression and p27(Kip1 (zeige CDKN1B Antikörper))-dependent proliferative expansion in response to antigen.

MAP3K7 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

mitogen-activated protein kinase kinase kinase 7 (map3k7) Antikörper
mitogen activated protein kinase kinase kinase 7 (Map3k7) Antikörper
mitogen-activated protein kinase kinase kinase 7 (MAP3K7) Antikörper
mitogen-activated protein kinase kinase kinase 7 (Map3k7) Antikörper

B430101B05 Antikörper
C87327 Antikörper
MEKK7 Antikörper
si:ch211-225h9.1 Antikörper
TAK1 Antikörper
TGF1a Antikörper
zgc:110612 Antikörper

Bezeichner auf Proteinebene für MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID	SPEZIES
553788	Danio rerio
313121	Rattus norvegicus
6885	Homo sapiens
26409	Mus musculus
529146	Bos taurus
100171454	Pongo abelii

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