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anti-Human ATF3 Antikörper:
anti-Mouse (Murine) ATF3 Antikörper:
anti-Rat (Rattus) ATF3 Antikörper:
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Human Polyclonal ATF3 Primary Antibody für IF (p), IHC (p) - ABIN669561
Hu, Li, Li: MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1. in PLoS ONE 2013
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Human Polyclonal ATF3 Primary Antibody für ICC, IF - ABIN4282009
Wu, Nguyen, Dziunycz, Chang, Brooks, Lefort, Hofbauer, Dotto: Opposing roles for calcineurin and ATF3 in squamous skin cancer. in Nature 2010
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Human Monoclonal ATF3 Primary Antibody für RNAi, ELISA - ABIN559974
Chen, Huang, Chu, Chen, Chou, Wang, Kulp, Teng, Wang, Chen: Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. in The Journal of biological chemistry 2011
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Human Polyclonal ATF3 Primary Antibody für IHC (p), IHC - ABIN315461
Maciag, Nandurdikar, Hong, Chakrapani, Diwan, Morris, Shami, Shiao, Anderson, Keefer, Saavedra: Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs. in Journal of medicinal chemistry 2011
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Human Monoclonal ATF3 Primary Antibody für ELISA, WB - ABIN559976
Hsueh, Kuo, Chen: Transcriptional regulators of the ?Np63: their role in limbal epithelial cell proliferation. in Journal of cellular physiology 2012
Human Polyclonal ATF3 Primary Antibody für FACS, WB - ABIN1536715
Mo, Dai, Kang, Cui, He et al.: Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal ... in The Journal of biological chemistry 2012
Data show that Atf3 was detected in retinal ganglion cell axons in both the nerve fiber layer and the optic nerve on the injured side.
Data show that ATF3 may be an important mediator of optic nerve regeneration-promoting gene expression in fish, a role which merits further investigation.
these data indicated that ATF3 might promote intestinal epithelial cell apoptosis in Crohn's disease via up-regulating the stability and transcription activity of p53 (zeige TP53 Antikörper)
electrophilic properties of itaconate and derivatives regulate the IkappaBzeta (zeige NFKBIZ Antikörper)-ATF3 inflammatory axis; results demonstrate that targeting the DI-IkappaBzeta (zeige NFKBIZ Antikörper) regulatory axis could be an important new strategy for the treatment of IL-17 (zeige IL17A Antikörper)-IkappaBzeta (zeige NFKBIZ Antikörper)-mediated autoimmune diseases
High ATF3 expression is associated with breast cancer.
ATF3 and EGR1 (zeige EGR1 Antikörper) are involved in the beginning of inflammatory processes. Whether these two transcription factors act as tumour suppressors or promoters is context dependent and warrants analysis in further studies
ATF3 and PRAP1 (zeige PRAP1 Antikörper) play important roles in cisplatin-induced DNA damage repair process.
Data show that amino acid limitation (amino acid response, AAR) activation of activating transcription factor 3 (ATF3) transcription is transient relative to activation by the unfolded protein response (UPR).
In patients with NAFLD (zeige TSC2 Antikörper) and/or T2D, a significant positive correlation was observed between hepatic ATF3 expression and surrogate markers of T2D, mitochondrial dysfunction, and macrophage infiltration.
our results suggest that ATF3 promotes the invasion and proliferation of CRC (zeige CALR Antikörper) cells, at least in part, via the regulation of CEACAM1 (zeige CEACAM1 Antikörper)-mediated EMT (zeige ITK Antikörper).
ATF3 is involved in promoting particulate matter-induced pulmonary inflammation.
Negative pressure wound therapy exerts an anti-inflammatory effect, possibly through the suppression of proinflammatory enzymes and cytokines resulting from Ik B-alpha inhibition and ATF-3 activation, which may prevent the activation of the NF-kappaB (zeige NFKB1 Antikörper) pathway in human diabetic foot wounds.
ATF3 in the host cells regulated a chemotherapeutic agent to immune modulation and cancer metastasis.
this study reveals a novel mechanism of naringenin through AMPK (zeige PRKAA1 Antikörper)-ATF3-dependent negative regulation of the LPS/TLR4 (zeige TLR4 Antikörper) signalling pathway, which thereby confers protection against murine endotoxaemia.
Conditional deletion of ATF3 in osteoclast precursors protects RANKL (zeige TNFSF11 Antikörper)-induced osteoclast activation and bone loss.
Data (including data from studies using mutant, transgenic, and knockout mice) suggest that gene targets of leptin/leptin (zeige LEP Antikörper)-receptor (zeige LEPR Antikörper) (Lep (zeige LEP Antikörper)/Lepr (zeige LEPR Antikörper)) signaling in hypothalamic neurons regulate energy metabolism; Lep (zeige LEP Antikörper)/Lepr (zeige LEPR Antikörper) signaling appears to up-regulate expression of Atf3 (activating transcription factor-3) in hypothalamic neurons.
ATF3 promotes macrophage migration and reverses M1polarized macrophages to the M2 phenotype by upregulation of TNC via the Wnt/betacatenin signaling pathway.
Microglia make contact through unknown neuronal signals regulated by ATF3 in hypoglossal nucleus.
ATF3 inhibit the expression and release of TNF-alpha (zeige TNF Antikörper), IL-1beta (zeige IL1B Antikörper), IL-6 (zeige IL6 Antikörper), and IL-18 (zeige IL18 Antikörper) induced by Mycoplasma pneumonia in vitro and in vivo, which is associated with its negative regulation of Egr-1 (zeige EGR1 Antikörper)/Fyn (zeige FYN Antikörper) signaling pathway.
ATF3 appears to affect gonadotropin-stimulated progesterone secretion at a step or steps downstream of PKA signaling and before cholesterol conversion to progesterone.
ATF3 induction by acute hypoxia is mediated by nitric oxide and the JNK (zeige MAPK8 Antikörper) pathway in endothelial cells
Data indicate increasing expression for CREB (zeige CREB1 Antikörper), ATF1 (zeige AFT1 Antikörper), and ATF3 during gastrulation.
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
cyclic AMP-dependent transcription factor ATF-3
, activating transcription factor 3
, cAMP-dependent transcription factor ATF-3
, transcription factor LRG-21
, liver regeneration factor 1