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MMP25 Produkte

(Matrix Metallopeptidase 25 (MMP25))
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008].

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Ausgewählte MMP25 Kategorien

MMP25 Antikörper

High quality antibodies with extensive validation data.

MMP25 ELISA Kits

Reliable ELISA kits for a wide range of species.

MMP25 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MMP25 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN7268422
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7258762
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN7242293
Menge 200 μL
Datenblatt Datenblatt

Empfohlene MMP25 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957696
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MMP25 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3083812
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3121955
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7395290
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MMP25 Produkten

Zhao, Sohail, Sun, Shi, Kim, Mobashery, Fridman: "Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25)." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 35023-32, (2008) (PubMed).

Sun, Weber, Sohail, Bernardo, Toth, Zhao, Turner, Fridman: "MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties." in: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 21998-2010, (2007) (PubMed).

Matsuda, Itoh, Koshikawa, Akizawa, Yana, Seiki: "Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36350-7, (2003) (PubMed).

Velasco, Cal, Merlos-Suárez, Ferrando, Alvarez, Nakano, Arribas, López-Otín: "Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors." in: Cancer research, Vol. 60, Issue 4, pp. 877-82, (2000) (PubMed).

Synonyme und alternative Namen zu MMP25

matrix metallopeptidase 25 (MMP25), matrix metallopeptidase 25 (Mmp25), F730048C11Rik, Leukolysin, MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6

Bezeichner auf Proteinebene für MMP25

  • leukolysin
  • matrix metallopeptidase-like 1
  • matrix metalloproteinase 20
  • matrix metalloproteinase 25
  • matrix metalloproteinase-25
  • matrix metalloproteinase-like 1
  • membrane-type 6 matrix metalloproteinase
  • membrane-type matrix metalloproteinase 6
  • membrane-type-6 matrix metalloproteinase
  • MMP-25
  • LOW QUALITY PROTEIN: matrix metalloproteinase-25
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