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MMP25 Antikörper

MMP25 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7242293
  • Target Alle MMP25 Antikörper anzeigen
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Reaktivität
    • 39
    • 21
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MMP25 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 15
    • 9
    • 6
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human MMP25
    Isotyp
    IgG
    Top Product
    Discover our top product MMP25 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Andere Bezeichnung
    MMP25 (MMP25 Produkte)
    Synonyme
    MMP-25 antikoerper, MMP20 antikoerper, MMP20A antikoerper, MMPL1 antikoerper, MT-MMP 6 antikoerper, MT-MMP6 antikoerper, MT6-MMP antikoerper, MT6MMP antikoerper, MTMMP6 antikoerper, F730048C11Rik antikoerper, Leukolysin antikoerper, matrix metallopeptidase 25 antikoerper, MMP25 antikoerper, Mmp25 antikoerper
    Hintergrund
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
    Molekulargewicht
    63 kDa
    NCBI Accession
    NP_071913
    UniProt
    Q9NPA2
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