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MMP25 Antikörper (AA 350-540)

MMP25 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7268422
  • Target Alle MMP25 Antikörper anzeigen
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Bindungsspezifität
    • 9
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 350-540
    Reaktivität
    • 39
    • 21
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MMP25 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 16
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Verwendungszweck
    MMP25 Rabbit pAb
    Sequenz
    SPRPARLHRF WEGLPAQVRV VQAAYARHRD GRILLFSGPQ FWVFQDRQLE GGARPLTELG LPPGEEVDAV FSWPQNGKTY LVRGRQYWRY DEAAARPDPG YPRDLSLWEG APPSPDDVTV SNAGDTYFFK GAHYWRFPKN SIKTEPDAPQ PMGPNWLDCP APSSGPRAPR PPKATPVSET CDCQCELNQA A
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human MMP25 (NP_071913.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    Andere Bezeichnung
    MMP25 (MMP25 Produkte)
    Synonyme
    MMP-25 antikoerper, MMP20 antikoerper, MMP20A antikoerper, MMPL1 antikoerper, MT-MMP 6 antikoerper, MT-MMP6 antikoerper, MT6-MMP antikoerper, MT6MMP antikoerper, MTMMP6 antikoerper, F730048C11Rik antikoerper, Leukolysin antikoerper, matrix metallopeptidase 25 antikoerper, MMP25 antikoerper, Mmp25 antikoerper
    Hintergrund
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.,MMP25,MMP-25,MMP20,MMP20A,MMPL1,MT-MMP 6,MT-MMP6,MT6-MMP,MT6MMP,MTMMP6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,MMP25
    Molekulargewicht
    62kDa
    Gen-ID
    64386
    UniProt
    Q9NPA2
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