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MKL1 Produkte

(Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Kategorien

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq, Jul 2008].

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Ausgewählte MKL1 Kategorien

MKL1 Antikörper

High quality antibodies with extensive validation data.

Empfohlene MKL1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7264553
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP
Validierungen
  • (3)
Kat. Nr. ABIN6143855
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Pig, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN1387286
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MKL1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968520
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MKL1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3093809
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136609
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MKL1 Produkten

Whitson, Lee, Urman, Mirza, Yao, Brown, Li, Shankar, Fry, Atwood, Lee, Hollmig, Aasi, Sarin, Scott, Epstein, Tang, Oro: "Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas." in: Nature medicine, Vol. 24, Issue 3, pp. 271-281, (2018) (PubMed).

Gjorevski, Piotrowski, Varner, Nelson: "Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices." in: Scientific reports, Vol. 5, pp. 11458, (2015) (PubMed).

Record, Malinova, Zenner, Plagnol, Nowak, Syed, Bouma, Curtis, Gilmour, Cale, Hackett, Charras, Moulding, Nejentsev, Thrasher, Burns: "Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1." in: Blood, Vol. 126, Issue 13, pp. 1527-35, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Schmidt, Duncan, Yadav, Regan, Verone, Lohse, Pop, Attwood, Wilding, Mohler, Sebo, Tindall, Heemers: "RhoA as a mediator of clinically relevant androgen action in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 5, pp. 716-35, (2012) (PubMed).

Muehlich, Hampl, Khalid, Singer, Frank, Breuhahn, Gudermann, Prywes: "The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1." in: Oncogene, Vol. 31, Issue 35, pp. 3913-23, (2012) (PubMed).

Synonyme und alternative Namen zu MKL1

megakaryoblastic leukemia (translocation) 1 (MKL1), megakaryoblastic leukemia 1 protein (mkl1), megakaryoblastic leukemia (translocation) 1 (Mkl1), megakaryoblastic leukemia (translocation) 1 S homeolog (mkl1.S), MKL (megakaryoblastic leukemia)/myocardin-like 1 (Mkl1), AI852829, AMKL, AW743281, AW821984, BSAC, Bsac, MAL, Mal, MKL1, MRTF-A, Mrtf-a, mrtf-a, Mrtf-A, mrtfa

Bezeichner auf Proteinebene für MKL1

  • megakaryoblastic leukemia 1 protein
  • MKL/myocardin-like protein 1
  • RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein
  • basic, SAP and coiled-coil domain
  • megakaryocytic acute leukemia protein
  • myocardin-related transcription factor A
  • xMRTF-A
  • basic SAP and coiled-coil domains
  • basic SAP coiled-coil transcription activator
  • megakaryoblastic leukemia (translocation) 1 homolog
  • megakaryoblastic leukemia 1 protein homolog
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