MKL1 Antikörper (AA 1-280)

Produktnummer ABIN6143855

Produktdetails anti-MKL1 Antikörper

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Bindungsspezifität: AA 1-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: MPPLKSPAAF HEQRRSLERA RTEDYLKRKI RSRPERSELV RMHILEETSA EPSLQAKQLK LKRARLADDL NEKIAQRPGP MELVEKNILP VESSLKEAII VGQVNYPKVA DSSSFDEDSS DALSPEQPAS HESQGSVPSP LEARVSEPLL SATSASPTQV VSQLPMGRDS REMLFLAEQP PLPPPPLLPP SLTNGTTIPT AKSTPTLIKQ SQPKSASEKS QRSKKAKELK PKVKKLKYHQ YIPPDQKQDR GAPPMDSSYA KILQQQQLFL QLQILNQQQQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MKL1 (NP_065882.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Andere Bezeichnung: MKL1 (MKL1 Produkte)

Synonyme: MKL1 antikoerper, BSAC antikoerper, MAL antikoerper, MRTF-A antikoerper, Mrtf-a antikoerper, mrtf-a antikoerper, mrtfa antikoerper, AI852829 antikoerper, AMKL antikoerper, AW743281 antikoerper, AW821984 antikoerper, Bsac antikoerper, Mal antikoerper, Mrtf-A antikoerper, megakaryoblastic leukemia (translocation) 1 antikoerper, megakaryoblastic leukemia 1 protein antikoerper, megakaryoblastic leukemia (translocation) 1 S homeolog antikoerper, MKL (megakaryoblastic leukemia)/myocardin-like 1 antikoerper, MKL1 antikoerper, mkl1 antikoerper, Mkl1 antikoerper, mkl1.S antikoerper

Hintergrund: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.,MKL1,BSAC,MAL,MRTF-A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cytoskeleton,Endocrine & Metabolism,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiogenesis,MKL1

Molekulargewicht: 98 kDa

Gen-ID: 57591

UniProt: Q969V6