MCM8 Proteine
(Minichromosome Maintenance Deficient 8 (MCM8))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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MCM8
Spezies: Human
Wirt: Wheat germ
Recombinant
ELISA, WB, AA, AP
1 image
MCM8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCM8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
ELISA, WB, SDS
custom-made
MCM8
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MCM8
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aktuelle Publikationen für unsere MCM8 Proteine
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).Aliase für MCM8 Proteine
minichromosome maintenance 8 homologous recombination repair factor (MCM8) Proteineminichromosome maintenance 8 homologous recombination repair factor (Mcm8) Proteine
minichromosome maintenance 8 homologous recombination repair factor L homeolog (mcm8.L) Proteine
5730432L01Rik Proteine
C20orf154 Proteine
dJ967N21.5 Proteine
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