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MC1 Receptor Proteine

(Melanocortin 1 Receptor (MC1R))
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008].

8 Treffer

custom-made MC1R Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7556860
 
custom-made MC1R Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7549573
 
MC1R Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Produktnummer ABIN7536623
 
MC1R Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Produktnummer ABIN1310505
 
MC1R Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc ELISA, cryo-EM, Imm, PhD, SPR
Produktnummer ABIN7596830
 
MC1R Spezies: Human Wirt: Mammalian Cells Synthetic Nanodisc
Produktnummer ABIN7538382
 
custom-made MC1R Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Produktnummer ABIN3121356
 
custom-made MC1R Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Produktnummer ABIN3099289
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Phage Display (PhD)
    • Surface Plasmon Resonance (SPR)
    • Cryogenic electron microscopy (cryo-EM)
  • Reaktivität
    • Human
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
    • Mammalian Cells
  • Bindungsspezifität
    • AA 1-317
    • AA 1-315
    • AA 1-100
  • Konjugat
    • GST tag
    • His tag
    • Strep Tag
    • DYKDDDDK Tag,Strep Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
    • Synthetic Nanodisc
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online

Aliase für MC1 Receptor Proteine

melanocortin 1 receptor (MC1R) Proteine
melanocortin 1 receptor (Mc1r) Proteine
melanocortin 1 receptor (mc1r) Proteine
melanocortin 1 receptor (mc1r_par1) Proteine
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) (MC1R) Proteine
CMM5 Proteine
e Proteine
MC1-R Proteine
mc1r Proteine
MC1R Proteine
MSH-R Proteine
MSHR Proteine
Mshra Proteine
SHEP2 Proteine
Tob Proteine
TUBB3 Proteine
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