Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Rat (Rattus) MAP3K1 Antikörper:
anti-Mouse (Murine) MAP3K1 Antikörper:
anti-Human MAP3K1 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal MAP3K1 Primary Antibody für DB - ABIN389719
Mokhtari, Myers, Welsh: MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells. in Diabetes 2008
Show all 2 Pubmed References
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 gene, which promotes FoxO1 (zeige FOXO1 Antikörper) expression and dephosphorylation with nuclear accumulation.
Data identify a unique signal crosstalk between Wnt (zeige WNT2 Antikörper) signaling and the MAP3K1-JNK (zeige MAPK8 Antikörper) pathway in epithelial morphogenesis.
These results reveal the importance of the MEKK1 (zeige MAP2K1 Antikörper)-calponin-3 (zeige CNN3 Antikörper) signaling pathway to cell contractility.
Map3k1 regulates iNKT cell proliferative expansion in response to glycolipid antigen
goya and kinase-deficient Map3k1 homozygotes initially develop supernumerary cochlear outer hair cells (OHCs) that subsequently degenerate.
These data highlight the crucial role of MAP3K1 in the development and function of the mouse inner ear and hearing.
Dioxin exposure markedly inhibited c-Jun (zeige JUN Antikörper) phosphorylation in Map3k1-deficient embryonic eyelid epithelium, suggesting that dioxin-induced AHR (zeige AHR Antikörper) pathways can synergize with gene mutations to inhibit MAP3K1 signaling.
Both the MEKK1 (zeige MAP2K1 Antikörper) PHD (zeige PDC Antikörper) and TAB1 (zeige TAB1 Antikörper) are critical for ES-cell differentiation
Results suggest that proto-oncogene (zeige RAB1A Antikörper) protiins c-Jun (zeige JUN Antikörper) and mitogen-activated protein 3 (zeige HSPB3 Antikörper) kinase 1 (MAP3K1) represent parallel pathways in the control of eyelid closure.
Aberrant expression of Map3k1 enabled growth factor-autonomous proliferation and drove BRAF (zeige BRAF Antikörper)-independent ERK (zeige EPHB2 Antikörper) signaling, thus shedding light on alternative means of activating this prominent signaling pathway in melanoma.
analysis of the gene expression program of MAP3K1 in mouse eyelid morphogenesis
double mekk1/camta3 mutant positioned CAMTA3 downstream of MEKK1 and verified their distinct roles in GSR (zeige GSR Antikörper) regulation. mekk1-5 displays programmed cell death and overaccumulates reactive oxygen species and salicylic acid
Treatment of Arabidopsis with a membrane rigidifier, DMSO, causes MPK4 (zeige MAPK4 Antikörper) activation concomitantly with MEKK1 and MKK2 (zeige MAP2K2 Antikörper) phosphorylation.
Ca(2 (zeige CA2 Antikörper)+) signaling occurred upstream of the MEKK1-MKK2 (zeige MAP2K2 Antikörper) pathway. MEKK1 was phosphorylated by calcium/calmodulin-regulated receptor-like kinase (CRLK1), which suggested that CRLK1 is one of candidates located upstream of MEKK1.
MEKK1 plays a key role in transducing the l-Glu (zeige DCTN1 Antikörper) signal that elicits large-scale changes in root architecture, and provide genetic evidence for the existence in plants of an external glutamate (zeige GRIN2A Antikörper) (l-Glu (zeige DCTN1 Antikörper)) signalling pathway analogous to that found in animals.
Data indicate that MEKK2 (zeige MAP3K2 Antikörper) is required for the mekk1, mkk1 (zeige MAP2K1 Antikörper) mkk2 (zeige MAP2K2 Antikörper), and mpk4 (zeige MAPK4 Antikörper) autoimmune phenotypes.
Data suggest that the MEKK1-MKK1 (zeige MAP2K1 Antikörper)/MKK2 (zeige MAP2K2 Antikörper)-MPK4 (zeige MAPK4 Antikörper) kinase cascade negatively regulates MEKK2 (zeige MAP3K2 Antikörper) and activation of MEKK2 (zeige MAP3K2 Antikörper) triggers SUMM2-mediated immune responses.
CRLK1 interacts with MEKK1 in vitro and in planta during cold treatment.
An analysis of the interation of MEKK1 and MEK1 (zeige MAP2K1 Antikörper) in response to wounding stress in A. thaliana seedlings is presented.
MEKK1 is essential for activation of MPK4 and negatively regulates temperature-sensitive and tissue-specific cell death and H(2)O(2) accumulation that are dependent on both RAR1 (resistance protein function) and SID2 (isochorismate synthase)
This study demonstrated that analysis of plants carrying T-DNA knockout alleles indicated that MEKK1 is required for flg22-induced activation of MPK4 (zeige MAPK4 Antikörper).
Through a stratification analysis, 5q11.2/MAP3K1 (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and 7q32.3/LINC-PINT (rs4593472) were associated with Luminal A, and 10q26.1/FGFR2 (zeige FGFR2 Antikörper) (rs35054928) was associated with Luminal B.
We have revealed significant association of FGFR2 (zeige FGFR2 Antikörper) and MAP3K1 polymorphisms with breast cancer.
Identification of a MAP3K1 variant should prompt an evaluation for disorders of sex development in female siblings of the proband
Polymorphism of MAP3K1 is associated with breast cancer.
SNP variants at the MAP3K1/SETD9 gene boundary associate with somatic PIK3CA (zeige PIK3CA Antikörper) variants in breast cancers.
CSN6 (zeige COPS6 Antikörper) positively regulates c-Jun (zeige JUN Antikörper) in a MEKK1-dependent manner
Mekk1 mediates p53 protein stability in the presence of Mdm2 and reduces p53 ubiquitination, suggesting an interference with Mdm2-mediated degradation of p53 by the ubiquitin-proteasome pathway.
BAALC (zeige BAALC Antikörper) conferred chemoresistance in acute myeloid leukemia (zeige BCL11A Antikörper) cells by upregulating ATP-binding cassette proteins in an ERK (zeige EPHB2 Antikörper)-dependent manner, which can be therapeutically targeted by MEK (zeige MAP2K1 Antikörper) inhibitor
MiR (zeige MLXIP Antikörper)-451 inhibited the proliferation of esophageal squamous cell carcinoma cells by targeting CDKN2D (zeige CDKN2D Antikörper) and MAP3K1 expression.
There were 3 specimens with mutations in MAP3K1 (MEKK1), including two truncation mutants, T779fs and T1481fs; T1481fs encoded an unstable and nonfunctional protein when expressed in vitro.
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.
mitogen-activated protein kinase kinase kinase 1
, MAPK/ERK kinase kinase 1
, MEK kinase 1
, MEKK 1
, mitogen activated protein kinase kinase kinase 1
, MAP/ERK kinase kinase 1