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anti-Human BCL2 Antikörper:
anti-Rat (Rattus) BCL2 Antikörper:
anti-Mouse (Murine) BCL2 Antikörper:
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Human Monoclonal BCL2 Primary Antibody für ICC, IHC (fro) - ABIN3044481
Jiang, Li, Zhou, Wang, Zhang, Wang: Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways. in International journal of molecular medicine 2014
Show all 91 Pubmed References
Human Polyclonal BCL2 Primary Antibody für ELISA, WB - ABIN3042814
Zong, Li, Lin, Hou, Ma: Lipoxin A4 pretreatment mitigates skeletal muscle ischemia-reperfusion injury in rats. in American journal of translational research 2017
Show all 79 Pubmed References
Human Polyclonal BCL2 Primary Antibody für IF, IHC (p) - ABIN388095
Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010
Show all 19 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IHC (fro), FACS - ABIN967312
Batistatou, Merry, Korsmeyer, Greene: Bcl-2 affects survival but not neuronal differentiation of PC12 cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1993
Show all 13 Pubmed References
Mouse (Murine) Monoclonal BCL2 Primary Antibody für FM, IHC (fro) - ABIN967441
Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991
Show all 10 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IHC (f), IHC (fro) - ABIN967321
Krajewski, Tanaka, Takayama, Schibler, Fenton, Reed: Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. in Cancer research 1993
Show all 7 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IHC (f), IHC (fro) - ABIN967322
Pezzella, Jones, Ralfkiaer, Ersbøll, Gatter, Mason: Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma. in British journal of cancer 1992
Show all 7 Pubmed References
Human Polyclonal BCL2 Primary Antibody für IF (p), IHC (p) - ABIN707156
Wang, Ma, Su: NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. in Biological trace element research 2013
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Dog (Canine) Polyclonal BCL2 Primary Antibody für IHC, IHC (p) - ABIN4283360
Chopra, Ray, Dwivedi, Tiwari, Singh, Singh, Kushwaha, Jahan, Pandey, Gupta, Chaturvedi, Pant, Ray, Gupta: Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line. in Biomaterials 2016
Show all 6 Pubmed References
Human Monoclonal BCL2 Primary Antibody für ICS - ABIN1177234
Deng, Xiao, Lang, Gao, Ruvolo, May: Novel role for JNK as a stress-activated Bcl2 kinase. in The Journal of biological chemistry 2001
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on the basis of data obtained during the study, it can be concluded that these polyphenols have the potential to be used as lead molecules for BCL-2 inhibition.
Tumor cell hypoxia induced Bcl-2/Twist1 (zeige TWIST1 Antikörper) complex formation, promoting tumor cell invasion in oral squamous cell carcinoma.
Bcl-2 rs1800477A/G polymorphism may be related to the occurrence of colorectal cancer(CRC (zeige CALR Antikörper)), and GG genotype could be a risk factor of poor prognosis in CRC (zeige CALR Antikörper).
BTK (zeige BTK Antikörper)-mediated signaling was found to be highly attenuated accompanied by a shift in PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) and apoptosis regulation-associated genes/proteins. Cytotoxicity studies using the AKT (zeige AKT1 Antikörper) inhibitor, MK2206+/-ibrutinib, and the Bcl-2-specific inhibitor, venetoclax+/-ibrutinib, demonstrated synergistic loss of cell viability
immunohistochemically defined cell remains a useful tool for predicting prognosis in diffuse large B-cell lymphoma when performed under optimized standardized conditions and that BCL2 expression may help to identify elderly patients at risk for relapse and who could potentially respond to anti-BCL2 targeted agents. . the coexpression of MYC (zeige MYC Antikörper) and BCL2 does not appear to predict worse survival
OHPg/PR-B (zeige PGR Antikörper) through Beclin-1 (zeige BECN1 Antikörper) and Bcl2 evoke autophagy-senescence transition in breast cancer cells
our data present preliminary evidence that inherited abnormalities in the intrinsic apoptosis pathway, related to BAX (zeige BAX Antikörper) G(-248)A and BCL2 C(-717)A SNPs, are associated with treatment response and act as independent prognostic factors in DLBCL.
BCL-2 expression is associated with oxidative stress and total antioxidant status in pediatric acute lymphoblastic leukemia.
A significant correlation between changes in the levels of expression and methylation was detected for the three apoptosis-regulatory genes (APAF1 (zeige APAF1 Antikörper), DAPK1 (zeige DAPK1 Antikörper), and BCL2). The results suggest that methylation play an important role in the regulation of the apoptosis system genes in breast cancer.
Overexpression of Bcl-2 is associated with Papillary Thyroid Carcinoma.
The findings support a model in which survival is determined by quantitative participation of multiple anti-apoptotic proteins, BCL2, Mcl1 (zeige MCL1 Antikörper), and BCL2A1 (zeige BCL2A1 Antikörper), rather than by a single anti-apoptotic protein.
Bcl-2 is strongly expressed in the inner hair cells and spiral ganglion neurons of young mice. In addition, moderate Bcl-2 expression is also detected in the outer hair cells and in the neurons of the auditory cortex. A significant reduction of Bcl-2 expression in the cochlea or auditory cortex is also associated with elevated hearing thresholds and hair cell loss during aging.
Bcl2 is the autophagy-related target of miR (zeige MLXIP Antikörper)-449a.
anti-apoptotic molecules BclxL (zeige BCL2L1 Antikörper) and Bcl-2 and the pro-apoptotic factors BAD and BID (zeige BID Antikörper) cooperate to promote migration of triple-negative breast cancer cells stimulated with cl-CD95L (zeige FASL Antikörper).
Acute ethanol exposure induced autophagy-mediated heart toxicity and injury mainly through the ROS (zeige ROS1 Antikörper)-JNK (zeige MAPK8 Antikörper)-Bcl-2 signaling pathway.
Th17 cells are resistant to glucocorticoid-induced apoptosis and cytokine suppression, at least in part due to high levels of BCL-2. These findings support a role of Th17 cells in glucocorticoid-resistant inflammatory conditions such as certain endotypes of asthma.
E2 protects skeletal myoblasts against apoptosis induced by H2 O2 modulating p53 (zeige TP53 Antikörper) and FoxO (zeige FOXO3 Antikörper) transcription factors and then their target genes Bcl-2, Bim (zeige BCL2L11 Antikörper), Puma (zeige BBC3 Antikörper), PERP (zeige PERP Antikörper), and MDM2 (zeige MDM2 Antikörper), without affecting Noxa (zeige PMAIP1 Antikörper) gene.
Bcl-2 expression has a significant impact on the mineralogical content of enamel crystals of tooth structure
The results suggest that CARP (zeige ANKRD1 Antikörper) can protect against hypoxia-reperfusion induced cardiomyocyte apoptosis, possibly through increasing anti-apoptosis Bcl2 gene expression.
This study provides evidence from transgenic mouse models that Crebbp (zeige CREBBP Antikörper) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.
These results suggest a role for mitochondrial p53 (zeige TP53 Antikörper) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (zeige BAX Antikörper) and Bcl2.
Zebrafish gene expressions of P53 (zeige TP53 Antikörper), Bcl-2, Bax (zeige BAX Antikörper) and caspase-3 (zeige CASP3 Antikörper) were elevated after exposure with microcystin-LR under different ambient temperatures.
Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (zeige S1PR1 Antikörper), and ICAM1 (zeige ICAM1 Antikörper) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.
Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (zeige COX2 Antikörper) and bcl2, but increased p53 (zeige TP53 Antikörper) expression.
Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (zeige NOTCH1 Antikörper) and fish bcl-2, indicating synergy between the Notch (zeige NOTCH1 Antikörper) pathway and the bcl2-mediated antiapoptotic pathway.
Over-expression of STC-1 (zeige STC1 Antikörper) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (zeige CASP3 Antikörper) production in the damaged cells. Findings from this study suggest that STC-1 (zeige STC1 Antikörper) plays a protective role in intestinal cells through an antioxidant mechanism.
BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (zeige BAX Antikörper) expression.
G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.
role of vascular endothelial growth factor receptor-1 (zeige FLT1 Antikörper) in Bcl-2 expression
apoptosis-inducing factor (zeige AIFM1 Antikörper) was expressed in luminal alveolar cells and, in concert with a change in bax (zeige BAX Antikörper) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
mRNA expression of Bax (zeige BAX Antikörper), Bcl-2, caspase-3 (zeige CASP3 Antikörper) and-7 cannot be used as a reliable apoptosis detection method.
These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.
bcl-2 and bax (zeige BAX Antikörper) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (zeige BAX Antikörper)]
excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (zeige CASP3 Antikörper) expression as well as low Bcl-2 expression.
These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (zeige BAX Antikörper) ratio through a mechanism involving protein kinase C (zeige PKC Antikörper).
Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (zeige BAX Antikörper) and decreasing expression of bcl2.
Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (zeige BAX Antikörper).
Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (zeige TP53 Antikörper) and decrease in the antiapoptotic BCl2 proteins.
Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (zeige CASP3 Antikörper).
Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
apoptosis regulator Bcl-2
, protein phosphatase 1, regulatory subunit 50
, B cell lymphoma 2 associated oncogene
, B-cell leukemia/lymphoma 2
, Bcl2-like protein
, BCL2B-cell CLL/lymphoma 2
, B-cell lymphoma protein 2
, B-cell CLL/lymphoma 2
, LOW QUALITY PROTEIN: apoptosis regulator Bcl-2
, Apoptosis regulator Bcl-2