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Together, our results suggest that KLF4 (zeige KLF4 Proteine) regulates asthma development in a TSLP (zeige TSLP Proteine)- and fibrocyte-dependent manner.
Pronounced correlations between KLK10 (zeige KLK10 Proteine)/KLK11 (rs = 0.647) and between KLK9 (zeige KLK9 Proteine)/KLK15 (zeige KLK15 Proteine) (rs = 0.716) mRNA, but not between other combinations, indicate coordinate expression of distinct pairs of peptidases
Variations in KLK15 (zeige KLK15 Proteine), but not KLK11 expression were significantly associated with prognosis in gastric cancer
KLK11 mRNA expression could be considered as a new molecular prognostic biomarker in colorectal adenocarcinoma
hK11 expression in gastric cancer appears to be associated with a better prognosis. hK11 may be a prognostic biomarker of gastric cancer.
The aim of this study was to monitor serum levels of two microRNAs (miR-21 and miR-141) and three kallikreins (hK3/PSA, hK11, and hK13) before and 1, 5, and 30 days after radical prostatectomy.
Our data showed that UVB-induced TSLP (zeige TSLP Proteine) might increase secretion of the T-helper type 2-attracting chemokine (c-c motif) ligand 17 (zeige CCL17 Proteine) by human dendritic cells.
HOXB8 (zeige HOXB8 Proteine) and KLK11 may be classified as valuable biomarkers, as they can predict the effects of FOLFOX4 chemotherapy in primary advanced colorectal cancer patients
Human airway trypsin-like protease (zeige TMPRSS11D Proteine) can stimulate mucin5AC hypersecretion through a PAR2 (zeige F2RL1 Proteine)-mediated signaling pathway in 16HBE cells.
Patients harboring KLK11-positive tumors had a significantly decreased risk of death.
Low KLK11 protein expression is associated with gastric cancer.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
kallikrein-related peptidase 11
, kallikrein 11
, protease, serine, 20
, serine protease 20
, trypsin-like protease