NGFB ELISA Kit

Produktnummer ABIN2042619

Dieses Human NGFB ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human NGFB zu quantifizieren.

Kurzübersicht für NGFB ELISA Kit (ABIN2042619)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 15.6-1000 pg/mL

Applikation: ELISA

Produktdetails NGFB ELISA Kit

Untere Nachweisgrenze: 15.6 pg/mL

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 1 pg/mL

Bestandteile: A: Microtiter Strip, 1x96 wells
B: NGF Standard, 2x10 ng
C: Anti-human NGF (Biotin), 1x130 µL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: NGF/NGF beta BioAssay-ELISA Kit, Human is a sandwich ELISA quantitative detection kit for human NGF/NGF beta in cell culture supernates and serum.Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male mouse submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF (1). NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis (2). The standard product used in this kit is human 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu NGFB

Target: NGFB (Nerve Growth Factor beta (NGFB))

Gen-ID: 4803

UniProt: P01138

Pathways: NF-kappaB Signalweg, RTK Signalweg, Regulation of Cell Size