MICB ELISA Kit
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- Target Alle MICB ELISA Kits anzeigen
- MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
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Reaktivität
- Human
- Nachweismethode
- Colorimetric
- Methodentyp
- Sandwich ELISA
- Detektionsbereich
- 62.5-4000 pg/mL
- Untere Nachweisgrenze
- 62.5 pg/mL
- Applikation
- ELISA
- Marke
- BioAssay™
- Kreuzreaktivität (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Sensitivität
- < 10 pg/mL
- Bestandteile
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96-well plate pre-coated with anti-MICB, Human
Lyophilized recombinant MICB, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL - Featured
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- Plattentyp
- Pre-coated
- Protokoll
- Sandwich ELISA quantitative detection kit for Human MICB in cell culture supernates, serum and plasma (heparin, EDTA).MHC class I polypeptide-related sequence B, also called MICB is a protein that in humans is encoded by the MICB gene. The MICB gene is mapped to 6p21.33. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. It seems to have no role in antigen presentation. This gene acts as a stress-induced self-antigen that is recognized by gamma delta T cells. It is the ligand for the KLRK1/NKG2D receptor and binds to KLRK1 leads to cell lysis.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- 4 °C/-20 °C
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- Target Alle MICB ELISA Kits anzeigen
- MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
- Andere Bezeichnung
- MICB (MICB Produkte)
- Synonyme
- PERB11.2 ELISA Kit, MHC class I polypeptide-related sequence B ELISA Kit, MHC class I-related protein-like ELISA Kit, MICB ELISA Kit, LOC512825 ELISA Kit
- Gen-ID
- 4277
- UniProt
- Q29980
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