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K-RAS Produkte

(GTPase Kras (KRAS))

Kategorien

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].

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Ausgewählte K-RAS Kategorien

K-RAS Antikörper

High quality antibodies with extensive validation data.

K-RAS ELISA Kits

Reliable ELISA kits for a wide range of species.

K-RAS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene K-RAS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (5)
  • (5)
Kat. Nr. ABIN561621
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN561622
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF, FACS
Validierungen
  • (7)
Kat. Nr. ABIN3031120
Menge 0.2 mL
Datenblatt Datenblatt

Empfohlene K-RAS ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962518
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956365
Menge 96 tests
Datenblatt Datenblatt

Empfohlene K-RAS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7319807
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123230
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123229
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren K-RAS Produkten

Chen, Lv, Shen, Wang, Tang, Xiong, Ding, Geng, Huang: "EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells." in: Acta pharmacologica Sinica, Vol. 41, Issue 2, pp. 270-277, (2020) (PubMed).

Riquelme, Behrens, Lin, Simon, Papadimitrakopoulou, Izzo, Moran, Kalhor, Lee, Minna, Wistuba: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." in: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).

Madureira, Bharadwaj, Bydoun, Garant, OConnell, Lee, Waisman: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).

Xu, Sun, Qin, Wang, Zheng, Xu, Luo, Liu, Liu, Du, Zhang, Liu, Ren: "Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 11, pp. 1686-97, (2015) (PubMed).

King, Bray, Galbraith, Christie, Fleming: "Evidence for aldosterone-dependent growth of renal cell carcinoma." in: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).

Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

Valtorta, Misale, Sartore-Bianchi, Nagtegaal, Paraf, Lauricella, Dimartino, Hobor, Jacobs, Ercolani, Lamba, Scala, Veronese, Laurent-Puig, Siena, Tejpar, Mottolese, Punt, Gambacorta, Bardelli et al.: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).

Kohli, Kaza, Coric, Byer, Brossier, Klocke, Bjornsti, Carroll, Roth: "4-Hydroxytamoxifen induces autophagic death through K-Ras degradation." in: Cancer research, Vol. 73, Issue 14, pp. 4395-405, (2013) (PubMed).

Mologni, Brussolo, Ceccon, Gambacorti-Passerini: "Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51449, (2012) (PubMed).

Fuentes-Calvo, Blázquez-Medela, Santos, López-Novoa, Martínez-Salgado: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." in: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).

Synonyme und alternative Namen zu K-RAS

KRAS proto-oncogene, GTPase (KRAS), v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (kras), KRAS proto-oncogene, GTPase (Kras), Kirsten rat sarcoma viral oncogene homolog (Kras), semicolonial-7 (smco-7), Ras family protein (PGTG_03066), GTPase KRas (Tsp_02666), GTPase KRas (Tsp_01642), GTPase KRas (rask), Kirsten rat sarcoma viral oncogene homolog S homeolog (kras.S), AI929937, C-K-RAS, c-Ki-ras, CFC2, K-ras, k-ras, K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Ki-ras, kras, Kras-2, kras-a, kras-b, KRAS1, Kras2, KRAS2, NS, NS3, p21, p21B, p21ras, ras, RASK2, rask2, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, zgc:85725

Bezeichner auf Proteinebene für K-RAS

  • GTPase KRas
  • fa04e08
  • fc14b12
  • fc23g10
  • fj89d12
  • xRAS2
  • K-Ras 2
  • Kirsten rat sarcoma viral oncogene homologue 2 (active)
  • c-K-ras
  • c-K-ras2 protein
  • c-Kirsten-ras proto-oncogene
  • ki-Ras
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • K-ras p21 protein
  • PR310 c-K-ras oncogene
  • c-Ki-ras
  • c-Kirsten-ras protein
  • cellular c-Ki-ras2 proto-oncogene
  • oncogene KRAS2
  • transforming protein p21
  • v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
  • Kirsten rat sarcoma oncogene 2, expressed
  • p21 protein
  • Kirsten rat sarcoma viral oncogene homolog S homeolog
  • ras protein
  • ras p21
  • Kirsten rat sarcoma viral oncogene homolog
  • Kirsten rat sarcoma viral (Kras-2) oncogene homolog
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