K-RAS Antikörper (AA 1-188)

Produktnummer ABIN561621

Produktdetails anti-K-RAS Antikörper

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Bindungsspezifität: AA 1-188

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser K-RAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant KRAS.

Sequenz: MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3B10-2F2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-K-RAS Antikörper (ABIN561621)

Madureira, Bharadwaj, Bydoun, Garant, OConnell, Lee, Waisman: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).

King, Bray, Galbraith, Christie, Fleming: "Evidence for aldosterone-dependent growth of renal cell carcinoma." in: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).

Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

Valtorta, Misale, Sartore-Bianchi, Nagtegaal, Paraf, Lauricella, Dimartino, Hobor, Jacobs, Ercolani, Lamba, Scala, Veronese, Laurent-Puig, Siena, Tejpar, Mottolese, Punt, Gambacorta, Bardelli et al.: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).

Fuentes-Calvo, Blázquez-Medela, Santos, López-Novoa, Martínez-Salgado: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." in: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).

Details zu K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung: KRAS (KRAS Produkte)

Synonyme: wu:fa04e08 antikoerper, wu:fc14b12 antikoerper, wu:fc23g10 antikoerper, wu:fj89d12 antikoerper, zgc:85725 antikoerper, Kras2 antikoerper, c-Ki-ras antikoerper, p21 antikoerper, C-K-RAS antikoerper, CFC2 antikoerper, K-RAS2A antikoerper, K-RAS2B antikoerper, K-RAS4A antikoerper, K-RAS4B antikoerper, KI-RAS antikoerper, KRAS1 antikoerper, KRAS2 antikoerper, NS antikoerper, NS3 antikoerper, RASK2 antikoerper, AI929937 antikoerper, K-ras antikoerper, Ki-ras antikoerper, Kras-2 antikoerper, p21B antikoerper, ras antikoerper, k-ras antikoerper, kras antikoerper, kras-a antikoerper, kras-b antikoerper, rask2 antikoerper, K-RAS antikoerper, p21ras antikoerper, KRAS proto-oncogene, GTPase antikoerper, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog antikoerper, Kirsten rat sarcoma viral oncogene homolog antikoerper, semicolonial-7 antikoerper, Ras family protein antikoerper, GTPase KRas antikoerper, Kirsten rat sarcoma viral oncogene homolog S homeolog antikoerper, KRAS antikoerper, kras antikoerper, Kras antikoerper, smco-7 antikoerper, PGTG_03066 antikoerper, Tsp_02666 antikoerper, Tsp_01642 antikoerper, rask antikoerper, kras.S antikoerper

Substanzklasse: Viral Protein

Hintergrund: Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2

Gen-ID: 3845