The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
IFNAR2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
IFNAR2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Zhang, Yin, Yang, Li, Xu, Chen, Liu, Yuan, Fang, Xiao, Wu, Xu, Chu, Katlinski, Katlinskaya, Guo, Wei, Wang, Liu, Fuchs: "A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 8, pp. 2038-2049, (2017) (PubMed).