IFNAR2 Protein (AA 22-242) (His tag)

Produktnummer ABIN5713534

Produktdetails

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-242

Spezies: Maus

Quelle: Hefe

Aufreinigungstag / Konjugat: Dieses IFNAR2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: SLETITPSAF DGYPDEPCTI NITIRNSRLI LSWELENKSG PPANYTLWYT VMSKDENLTK VKNCSDTTKS SCDVTDKWLE GMESYVVAIV IVHRGDLTVC RCSDYIVPAN APLEPPEFEI VGFTDHINVT MEFPPVTSKI IQEKMKTTPF VIKEQIGDSV RKKHEPKVNN VTGNFTFVLR DLLPKTNYCV SLYFDDDPAI KSPLKCIVLQ PGQESGLSES A

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Andere Bezeichnung: INAR2 (IFNAR2 Produkte)

Synonyme: AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein

Hintergrund: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity .

Molekulargewicht: 26.76 kDa

UniProt: O35664

Pathways: JAK-STAT Signalweg, Hepatitis C