anti-NCOA1 (NCOA1) Antikörper

Bezeichnung:: anti-Nuclear Receptor Coactivator 1 Antikörper (NCOA1)

Auf www.antikoerper-online.de finden Sie aktuell 126 Nuclear Receptor Coactivator 1 (NCOA1) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NCOA1 Proteine (9) und NCOA1 Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 145 NCOA1 Produkte verfügbar.

Synonyme:: bHLHe42, bHLHe74, F-SRC-1, KAT13A, NCOA1, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRC-1, SRC1

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	NCOA1	8648	Q15788
	NCOA1	17977	P70365
	NCOA1	313929
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human NCOA1 Antikörper:

anti-Mouse (Murine) NCOA1 Antikörper:

anti-Rat (Rattus) NCOA1 Antikörper:

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Am meisten referenzierte anti-NCOA1 Antikörper

Human Monoclonal NCOA1 Primary Antibody für BI, WB - ABIN968842 : Oñate, Tsai, Tsai, OMalley: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. in Science (New York, N.Y.) 1995 (PubMed)
Show all 4 Pubmed References
Human Monoclonal NCOA1 Primary Antibody für ChIP, IF - ABIN152353 : Klinge, Jernigan, Mattingly, Risinger, Zhang: Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors alpha and beta by coactivators and corepressors. in Journal of molecular endocrinology 2004 (PubMed)
Show all 4 Pubmed References
Amphibian Polyclonal NCOA1 Primary Antibody für FACS, ICC - ABIN152700 : Rogatsky, Zarember, Yamamoto: Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. in The EMBO journal 2001 (PubMed)
Show all 3 Pubmed References
Human Polyclonal NCOA1 Primary Antibody für WB - ABIN151779 : Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: Androgen modulation of coregulator expression in prostate cancer cells. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

Weitere Antikörper gegen NCOA1 Interaktionspartner

Human Nuclear Receptor Coactivator 1 (NCOA1) Interaktionspartner

Our findings directly associate the AR/NCOA1 complex with PRKD1 (zeige PRKD1 Antikörper) regulation and cellular migration and support the concept of therapeutic inhibition of NCOA1 in prostate cancer.
SRC-1 (zeige SRC Antikörper) can impact osteoblast function in an estrogen receptor (zeige ESR1 Antikörper)-independent manner.
The pregnane X receptor (zeige NR1I2 Antikörper) down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 (zeige SRC Antikörper) coactivator.
miR (zeige MLXIP Antikörper)-4443 acts in a tumor-suppressive manner by down-regulating TRAF4 (zeige TRAF4 Antikörper) and NCOA1 downstream of MEK (zeige MAP2K1 Antikörper)-C/EBP (zeige CEBPA Antikörper)-mediated leptin (zeige LEP Antikörper) and insulin (zeige INS Antikörper) signaling, and that insulin (zeige INS Antikörper) and/or leptin (zeige LEP Antikörper) resistance (e.g. in obesity) may suppress this pathway and increase the risk of metastatic CRC (zeige CALR Antikörper).
Results provide the first evidence that NCOA1 is a direct target of miR (zeige MLXIP Antikörper)-105-1 suggesting that NCOA1 and miR (zeige MLXIP Antikörper)-105-1 may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of HCC (zeige FAM126A Antikörper) patients.
Data suggest that steroid receptor (zeige ESR2 Antikörper) coactivators (NCOA1, NCOA2 (zeige NCOA2 Antikörper), NCOA3 (zeige NCOA3 Antikörper)) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (zeige ESR2 Antikörper) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]
The mechanism of IL-6-induced AR activation is mediated through enhancing AR-SRC-1 interaction and inhibiting AR-SMRT interaction.
IL-6-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 and SMRT to the AR in a ligand-independent manner
NCOA1 potentiates breast cancer angiogenesis through upregulating HIF1alpha (zeige HIF1A Antikörper) and AP-1 (zeige FOSB Antikörper)-mediated VEGFa (zeige VEGFA Antikörper) expression
miR (zeige MLXIP Antikörper)-137 has a role in targeting p160 (zeige MSH6 Antikörper) steroid receptor (zeige ESR2 Antikörper) coactivators SRC1 (zeige SRC Antikörper), SRC2 (zeige NCOA2 Antikörper), and SRC3 (zeige NCOA3 Antikörper) and inhibits cell proliferation

Mouse (Murine) Nuclear Receptor Coactivator 1 (NCOA1) Interaktionspartner

SRC-1 can impact osteoblast function in an estrogen receptor (zeige ESR1 Antikörper)-independent manner.
The results suggest that biochanin A activates RORgamma-dependent IL-17 (zeige IL17A Antikörper) transcription through the enhancement of STAT3 (zeige STAT3 Antikörper) phosphorylation and STAT3 (zeige STAT3 Antikörper)-mediated recruitment of NCOA1 to RORgamma.
ubiquitination of K446 limits RORgammat-mediated Th17 differentiation by inhibiting the recruitment of coactivator SRC1
Loss of SRC-1 is associated with high Blood Pressure and Aortic Stiffness.
local E2 inhibition could induce aberrant actin polymerization and also showed an important role of SRC-1 in the mediation of local E2 action on hippocampal synaptic plasticity by regulation of actin cytoskeleton dynamics
SRC-1/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (zeige SLC12A3 Antikörper)-like abnormalities in the hearts of newborn and adult mice.
While hippocampal SRC-1 was significantly downregulated by orchidectomy (ORX), its expression was rescued by treatment with testosterone in a dose-dependent manner. Testosterone regulates synaptic proteins involves AR, estrogen receptors and SRC-1.
fetal lungs produce signals to initiate labor when mature, and SRC-1/-2-dependent production of SP-A (zeige SFTPA1 Antikörper) and PAF (zeige PAF Antikörper) is crucial for this process
Consequently, SRC-1 null mice displayed low TAT (zeige TAT Antikörper) expression and presented with hypertyrosinemia and corneal alterations, 2 clinical features observed in the human syndrome of TAT (zeige TAT Antikörper) deficiency.
the effect of orchidectomy (ORX) on the expression of SRC-1

Pig (Porcine) Nuclear Receptor Coactivator 1 (NCOA1) Interaktionspartner

we cloned and sequenced full length cDNA of NCOA-1 gene in pig. The putative protein includes 1440 amino acids. Sequences alignment showed that pig NCOA-1 gene cDNA sequence has identity of 93.73% with human and mouse.

NCOA1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with NCOA1

nuclear receptor coactivator 1 (NCOA1) Antikörper
nuclear receptor coactivator 1 (ncoa1) Antikörper
nuclear receptor coactivator 1 (Ncoa1) Antikörper

bHLHe42 Antikörper
bHLHe74 Antikörper
F-SRC-1 Antikörper
KAT13A Antikörper
NCOA1 Antikörper
RIP160 Antikörper
si:dkey-5g7.6 Antikörper
si:dkey-34f16.6 Antikörper
SRC-1 Antikörper
SRC1 Antikörper

Bezeichner auf Proteinebene für NCOA1

Hin-2 protein , PAX3/NCOA1 fusion protein , class E basic helix-loop-helix protein 74 , renal carcinoma antigen NY-REN-52 , steroid receptor coactivator-1 , nuclear receptor coactivator 1 , steroid receptor coactivator 1 , DKEY-34F16.7 , SRC1 , NCoA-1 , SRC-a/NCoA-1 , mNRC-1 , nuclear receptor coactivator protein 1 , SRC-1

GENE ID	SPEZIES
8648	Homo sapiens
422016	Gallus gallus
475684	Canis lupus familiaris
525346	Bos taurus
563288	Danio rerio
459068	Pan troglodytes
100025270	Monodelphis domestica
100385756	Callithrix jacchus
100471908	Ailuropoda melanoleuca
100556605	Anolis carolinensis
17977	Mus musculus
313929	Rattus norvegicus
574068	Sus scrofa
100722913	Cavia porcellus

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