Protein Überblick

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with Integrin beta 4 (ITGB4)

• integrin subunit beta 4 (ITGB4) Antikörper
• integrin beta 4 (Itgb4) Antikörper
• integrin subunit beta 4 (Itgb4) Antikörper

• AA407042 Antikörper
• C230078O20 Antikörper
• CD104 Antikörper

Bezeichner auf Proteinebene für ITGB4

integrin beta 4 , integrin beta-4 , CD104 antigen , GP150 , integrin beta-4 subunit