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Phenylbutyrate Na

Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

/ (Phenylbutyrate Na)

1 image

Produktnummer ABIN7233276

Kurzübersicht für Phenylbutyrate Na (ABIN7233276)

Applikation

Inhibition (Inh)

Chemical Name

4-Phenylbutyric acid, sodium salt

Verwendungszweck

HDAC inhibitor

Produktmerkmale

Chemical chaperone for misfolded proteins. Resolves ER stress in neuronal cells by aiding protein folding in the ER. Counteracts impaired glucose homeostasis in a mouse model of type 2 diabetes by preventing islet amyloid formation. Attenuates atherosclerotic progression and stabilizes existing plaques in mouse model of atherosclerosis via inhibition of ER stress. Protects against amyloid β-induced neurotoxicity in a mouse model. Weak histone deacetylase (HDAC) inhibitor which inhibits glioma cell proliferation. Active in vivo.

Reinheit

>98 %

Formel

C10H11O2 • Na

Löslichkeit

Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

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AS-8351
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Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Powder

Lagerung

RT
Hintergrund

4-PB, PBNa,Proliferation,Epigenetics,Posttranslational modification,Cell migration,Protein deacetylase,ER/Golgi,Cellular stress,Cell death,Stem cells,Atherosclerosis,Diabetes,Apoptosis inducer,Neurodegeneration,Chromatin

Molekulargewicht

186.2

CAS-Nummer

1716-12-7

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