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ING3 Proteine

(Inhibitor of Growth Family, Member 3 (ING3))
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008].

Häufig verwendete ING3 Proteine

Aliase für ING3 Proteine

inhibitor of growth family member 3 (ING3) Proteine
inhibitor of growth family, member 3 (Ing3) Proteine
inhibitor of growth protein 3 (CpipJ_CPIJ009396) Proteine
inhibitor of growth family, member 3 (ing3) Proteine
inhibitor of growth family member 3 L homeolog (ing3.L) Proteine
1300013A07Rik Proteine
Eaf4 Proteine
ING2 Proteine
ING3 Proteine
MEAF4 Proteine
p47ING3 Proteine
P47ING3 Proteine
zgc:56327 Proteine
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