Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

IL12 Proteine

(Interleukin 12 (IL12))
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].

42 Treffer

IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Produktnummer ABIN7274898
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274899
 
IL12 Spezies: Human Wirt: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018013
 
IL12 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274908
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN2181328
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Produktnummer ABIN6973104
 
IL12 Spezies: Maus Wirt: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Produktnummer ABIN7320573
 
IL12 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, AcA Active
Produktnummer ABIN5853918
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7317148
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7491453
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7455632
 
Rockland 010-001-v51-0010 IL12 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant 95,00% SDS
Produktnummer ABIN6700020
Rockland Original
Rockland 010-001-v51-0100 IL12 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant 95,00% SDS
Produktnummer ABIN6700021
Rockland Original
IL12 Spezies: Human Recombinant BCA
Produktnummer ABIN1111712
 
IL12 Spezies: Human Wirt: HEK-293T Cells Recombinant > 95 %, as determined by SDS-PAGE Active
Produktnummer ABIN1684636
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % (SDS-PAGE) Active
Produktnummer ABIN7566183
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505604
 
IL12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505595
 
IL12 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7454148
 
IL12 Spezies: Ratte Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Produktnummer ABIN2018061
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Activity Assay (AcA)
    • Biochemical Assay (BCA)
    • ELISA
    • Flow Cytometry (FACS)
    • Western Blotting (WB)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Mass Spectrometry (MS)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Cynomolgus
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Preservative free only
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • CHO Cells
    • Escherichia coli (E. coli)
    • Human Cells
    • Insect Cells
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
  • Bindungsspezifität
    • AA 23-328
    • AA 23-215
    • AA 23-335
    • AA 57-253
    • AA 23-219
    • AA 1-335
    • AA 1-219
    • C-Term
    • Extracellular Domain
  • Konjugat
    • Unkonjugiert
    • His tag
    • Fc Tag
    • Fc-His Tag
    • His tag,AVI tag,DYKDDDDK Tag,Biotin
    • His tag,DYKDDDDK Tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • Animal-Free
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • Rockland
    • BD Biosciences
    • Biospes
    • Cohesion Biosciences
    • ITSI-Biosciences

Aktuelle Publikationen für unsere IL12 Proteine

Ling, Gately, Gubler, Stern, Lin, Hollfelder, Su, Pan, Hakimi: "Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 1, pp. 116-27, (1995) (PubMed).

DAndrea, Aste-Amezaga, Valiante, Ma, Kubin, Trinchieri: "Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1041-8, (1993) (PubMed).

Schoenhaut, Chua, Wolitzky, Quinn, Dwyer, McComas, Familletti, Gately, Gubler: "Cloning and expression of murine IL-12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 11, pp. 3433-40, (1992) (PubMed).

DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

Aliase für IL12 Proteine

interleukin 12B (IL12B) Proteine
interleukin 12A (IL12A) Proteine
interleukin 12b (Il12b) Proteine
interleukin 12B (Il12b) Proteine
interleukin 12a (Il12a) Proteine
interleukin 12A (Il12a) Proteine
Interleukin 12 level (IL12) Proteine
interleukin 12a (il12a) Proteine
CLMF Proteine
CLMF2 Proteine
IL-12 Proteine
IL-12 p35 Proteine
Il-12a Proteine
IL-12B Proteine
Il-12b Proteine
IL-12p35 Proteine
Il-12p40 Proteine
IL-12p40 Proteine
Il12 Proteine
IL12B Proteine
Il12p40 Proteine
IL12p40 Proteine
Ll12a Proteine
LOC100217488 Proteine
NKSF Proteine
NKSF2 Proteine
p35 Proteine
p40 Proteine
Sie sind hier:
Chat with us!