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IL-15 Produkte

(Interleukin 15 (IL15))

Kategorien

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011].

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Ausgewählte IL-15 Kategorien

IL-15 Antikörper

High quality antibodies with extensive validation data.

IL-15 ELISA Kits

Reliable ELISA kits for a wide range of species.

IL-15 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IL-15 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7430678
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN517140
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7430681
Menge 100 μL
Datenblatt Datenblatt

Empfohlene IL-15 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6957032
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6957033
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6957034
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IL-15 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (5)
Kat. Nr. ABIN7274953
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (3)
Kat. Nr. ABIN6239761
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123549
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IL-15 Produkten

Zhuang, Yi, Chen, Kang, Chen, Chen, Cui, Chang, Ye, Ni, Wang, Du, Li, Liu, Jian, Li, Gao, Li, Li: "Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion." in: Cell death & disease, Vol. 11, Issue 6, pp. 453, (2020) (PubMed).

Wu, Wu, Ye, Yu, He, Chen: "Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 255, pp. 81-93, (2018) (PubMed).

Molanouri Shamsi, Chekachak, Soudi, Quinn, Ranjbar, Chenari, Yazdi, Mahdavi: "Combined effect of aerobic interval training and selenium nanoparticles on expression of IL-15 and IL-10/TNF-α ratio in skeletal muscle of 4T1 breast cancer mice with cachexia." in: Cytokine, Vol. 90, pp. 100-108, (2018) (PubMed).

Akieda-Asai, Ida, Miyazato, Kangawa, Date: "Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes." in: Peptides, Vol. 99, pp. 14-19, (2018) (PubMed).

Rekik, Smiti Khanfir, Larbi, Zamali, Beldi-Ferchiou, Kammoun, Marzouki, Hamzaoui, Mrad, Barbouche, Houman, Ben Ahmed: "Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22." in: Cytokine, Vol. 108, pp. 182-189, (2018) (PubMed).

Pangrazzi, Meryk, Naismith, Koziel, Lair, Krismer, Trieb, Grubeck-Loebenstein: ""Inflamm-aging" influences immune cell survival factors in human bone marrow." in: European journal of immunology, Vol. 47, Issue 3, pp. 481-492, (2017) (PubMed).

Gorvel, Korenfeld, Tung, Klechevsky: "Dendritic Cell-Derived IL-32α: A Novel Inhibitory Cytokine of NK Cell Function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1290-1300, (2017) (PubMed).

Ciccocioppo, Gallia, Avanzini, Betti, Picone, Vanoli, Paganini, Biagi, Maccario, Corazza: "A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions." in: Mayo Clinic proceedings, Vol. 91, Issue 6, pp. 812-9, (2016) (PubMed).

Shi, Liu, Zhang, Guo, Song, Song, Liu: "miR-15b is Downregulated in Myasthenia Gravis Patients and Directly Regulates the Expression of Interleukin-15 (IL-15) in Experimental Myasthenia Gravis Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1774-80, (2015) (PubMed).

Collignon, Perles-Barbacaru, Robert, Silvy, Martinez, Crenon, Germain, Garcia, Viola, Lombardo, Mas, Béraud: "A pancreatic tumor-specific biomarker characterized in humans and mice as an immunogenic onco-glycoprotein is efficient in dendritic cell vaccination." in: Oncotarget, Vol. 6, Issue 27, pp. 23462-79, (2015) (PubMed).

Synonyme und alternative Namen zu IL-15

interleukin 15 (IL15), interleukin 15 (Il15), AI503618, IL-15, IL15

Bezeichner auf Proteinebene für IL-15

  • interleukin 15
  • interleukin-15
  • IL-15
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