IKZF3 Produkte
(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
Kategorien
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte IKZF3 Kategorien
IKZF3 Antikörper
High quality antibodies with extensive validation data.
IKZF3 ELISA Kits
Reliable ELISA kits for a wide range of species.
IKZF3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IKZF3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7267842
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN564938
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN524769
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene IKZF3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975069
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IKZF3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307656
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3081893
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131337
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IKZF3 Produkten
: "Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4." in: Blood cancer journal, Vol. 9, Issue 2, pp. 19, (2019) (PubMed).: "Potent antitumor effect of combination therapy with sub-optimal doses of Akt inhibitors and pomalidomide plus dexamethasone in multiple myeloma." in: Oncology letters, Vol. 15, Issue 6, pp. 9450-9456, (2018) (PubMed).
: "p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 14, pp. 3565-3571, (2017) (PubMed).
: "Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase." in: The Journal of biological chemistry, Vol. 292, Issue 9, pp. 3683-3691, (2017) (PubMed).
: "Selective degradation of splicing factor CAPERα by anticancer sulfonamides." in: Nature chemical biology, Vol. 13, Issue 6, pp. 675-680, (2017) (PubMed).
: "Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties." in: Oncotarget, Vol. 8, Issue 32, pp. 53053-53067, (2017) (PubMed).
: "Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma." in: Blood, Vol. 124, Issue 4, pp. 536-45, (2014) (PubMed).
: "Ikaros family transcription factors in chronic and acute leukemia." in: American journal of hematology, Vol. 84, Issue 6, pp. 375-7, (2009) (PubMed).
: "Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits." in: Immunity, Vol. 26, Issue 3, pp. 335-44, (2007) (PubMed).
Synonyme und alternative Namen zu IKZF3
IKAROS family zinc finger 3 (IKZF3), IKAROS family zinc finger 3 L homeolog (ikzf3.L), IKAROS family zinc finger 3 (Ikzf3), 5830411O07Rik, AIO, aio, AIOLOS, aiolos, Aiolos, IKZF3, Zfpn1a3, ZNFN1A3, znfn1a3, Znfn1a3Bezeichner auf Proteinebene für IKZF3
- zinc finger protein Aiolos
- zinc finger protein, subfamily 1A, 3 (Aiolos)
- lymphoid transcription factor
- IKAROS family zinc finger 3 (Aiolos)
- ikaros family zinc finger protein 3
- zinc finger protein Aiolos-like
Sie sind hier:
