HPV16 E7 Produkte
(Human Papilloma Virus 16 E7 (HPV-16 E7))
Kategorien
E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
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Ausgewählte HPV16 E7 Kategorien
HPV16 E7 Antikörper
High quality antibodies with extensive validation data.
HPV16 E7 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HPV16 E7 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human Papillomavirus (HPV)
Applikation
WB, ELISA, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN5576956
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human Papillomavirus 16 (HPV-16)
Applikation
WB, IF (p), ELISA, FACS, IF (cc), IHC (p), IHC (fro), ICC
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN2173795
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human Papillomavirus 16 (HPV-16), Virus
Applikation
WB, IF (p), IHC (p)
Validierungen
Kat. Nr.
ABIN1713352
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HPV16 E7 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human papillomavirus type 52
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5710924
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human Papillomavirus 18 (HPV-18)
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5711077
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human Papillomavirus 18 (HPV-18)
Source
Yeast
Validierungen
- (1)
Kat. Nr.
ABIN5714208
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HPV16 E7 Produkten
: "Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth." in: International journal of oncology, Vol. 50, Issue 6, pp. 2011-2023, (2017) (PubMed).: "HPV16 E6/E7 upregulates HIF-2α and VEGF by inhibiting LKB1 in lung cancer cells." in: Tumour biology, Vol. 39, Issue 7, pp. 1010428317717140, (2017) (PubMed).
: "E6 and E7 oncoproteins from human papillomavirus type 16 induce activation of human transforming growth factor beta1 promoter throughout Sp1 recognition sequence." in: Viral immunology, Vol. 19, Issue 3, pp. 468-80, (2006) (PubMed).
: "Professionalism and team care in the clinical setting." in: Clinical anatomy (New York, N.Y.), Vol. 19, Issue 5, pp. 468-72, (2006) (PubMed).
: "Analysis of E7/Rb associations." in: Methods in molecular medicine, Vol. 119, pp. 363-79, (2005) (PubMed).
Synonyme und alternative Namen zu HPV16 E7
transforming protein E7 (E7)Bezeichner auf Proteinebene für HPV16 E7
- transforming protein
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